Mesterolone
Mesterolone structure
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Common Name | Mesterolone | ||
|---|---|---|---|---|
| CAS Number | 1424-00-6 | Molecular Weight | 304.467 | |
| Density | 1.1±0.1 g/cm3 | Boiling Point | 420.3±45.0 °C at 760 mmHg | |
| Molecular Formula | C20H32O2 | Melting Point | 208 °C | |
| MSDS | Chinese USA | Flash Point | 179.4±21.3 °C | |
| Symbol |
GHS07 |
Signal Word | Warning | |
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An updated steroid benchmark set and its application in the discovery of novel nanomolar ligands of sex hormone-binding globulin.
J. Med. Chem. 51 , 2047-56, (2008) A benchmark data set of steroids with known affinity for sex hormone-binding globulin (SHBG) has been widely used to validate popular molecular field-based QSAR techniques. We have expanded the data set by adding a number of nonsteroidal SHBG ligands identifi... |
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Screening for anabolic steroids in urine of forensic cases using fully automated solid phase extraction and LC-MS-MS.
J. Anal. Toxicol. 38(9) , 637-44, (2014) A screening method for 18 frequently measured exogenous anabolic steroids and the testosterone/epitestosterone (T/E) ratio in forensic cases has been developed and validated. The method involves a fully automated sample preparation including enzyme treatment,... |
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Osteoporosis in male hypogonadism: responses to androgen substitution differ among men with primary and secondary hypogonadism.
Horm. Res. 60(1) , 21-8, (2003) No randomized study exists comparing the effects of different modes of androgen substitution on bone mineral density (BMD).We performed a prospective, randomized, trial assigning 53 hypogonadal men to the following treatment groups: mesterolone 100 mg p.o. da... |
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Influence of various modes of androgen substitution on serum lipids and lipoproteins in hypogonadal men.
Metab. Clin. Exp. 48(5) , 590-6, (1999) We investigated whether the androgen type or application mode or testosterone (T) serum levels influence serum lipids and lipoprotein levels differentially in 55 hypogonadal men randomly assigned to the following treatment groups: mesterolone 100 mg orally da... |
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Metabolic studies of mesterolone in horses.
Anal. Chim. Acta 596(1) , 149-55, (2007) Mesterolone (1alpha-methyl-5alpha-androstan-17beta-ol-3-one) is a synthetic anabolic androgenic steroid (AAS) with reported abuses in human sports. As for other AAS, mesterolone is also a potential doping agent in equine sports. Metabolic studies on mesterolo... |
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Short-term treatment in sexual dysfunction: a review.
Compr. Psychiatry 22(2) , 206-17, (1981)
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The methyl-5 alpha-dihydrotestosterones mesterolone and drostanolone; gas chromatographic/mass spectrometric characterization of the urinary metabolites.
J. Steroid Biochem. Mol. Biol. 42(3-4) , 411-9, (1992) Before including the detection of the methyl-5 alpha-dihydrotestosterones mesterolone (1 alpha-methyl-17 beta-hydroxy-5 alpha-androstan-3-one) and drostanolone (2 alpha-methyl-17 beta-hydroxy-5 alpha-androstan-3-one) in doping control procedures, their urinar... |
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Effect of high intensity aerobic exercise and mesterolone on remodeling of Achilles tendon of C57BL/6 transgenic mice.
Cell Tissue Res. 339(2) , 411-20, (2010) The effect of mesterolone and intensive treadmill training (6 weeks, 5 days/week, means: 15.82 m/min and 45.8 min/day) in Achilles tendon remodeling was evaluated. Sedentary mice treated with mesterolone (Sed-M) or vehicle (Sed-C, placebo/control) and corresp... |
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Morphological changes in murine skeletal muscle in response to exercise and mesterolone.
J. Electron Microsc. (Tokyo) 59(2) , 153-64, (2010) Light and electron microscopy and quantitative morphometry were used to determine the effects of exercise and mesterolone on the soleus muscles of mice. Both exercise and mesterolone caused a significant hypertrophy of extrafusal muscle fibres. The hypertroph... |
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Regulation of neuronal and endothelial nitric oxide synthase by anabolic-androgenic steroid in skeletal muscles.
Histol. Histopathol. 27(11) , 1449-58, (2012) Anabolic-androgenic steroids (AAS) and exercise share comparable effects on myogenic differentiation, force development, fiber growth and skeletal muscle plasticity. The participation of nitric oxide synthase (NOS) on these effects was only demonstrated in re... |