Mast Cell Degranulating (MCD) Peptide
Mast Cell Degranulating (MCD) Peptide structure
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Common Name | Mast Cell Degranulating (MCD) Peptide | ||
|---|---|---|---|---|
| CAS Number | 17466-45-4 | Molecular Weight | 788.86800 | |
| Density | 1.51g/cm3 | Boiling Point | 1370.5ºC at 760mmHg | |
| Molecular Formula | C35H48N8O11S | Melting Point | N/A | |
| MSDS | Chinese USA | Flash Point | 782.6ºC | |
| Symbol |
GHS06 |
Signal Word | Danger | |
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The Qdot-labeled actin super-resolution motility assay measures low-duty cycle muscle myosin step size.
Biochemistry 52(9) , 1611-21, (2013) Myosin powers contraction in heart and skeletal muscle and is a leading target for mutations implicated in inheritable muscle diseases. During contraction, myosin transduces ATP free energy into the work of muscle shortening against resisting force. Muscle sh... |
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Ionomycin causes susceptibility to phospholipase A2 while temperature-induced increases in membrane fluidity fail: possible involvement of actin fragmentation.
Biochim. Biophys. Acta 1838(10) , 2607-14, (2014) A diminution in the order of membrane lipids, which occurs during apoptosis, has been shown to correlate with increased membrane susceptibility to hydrolysis by secretory phospholipase A2. Studies with artificial membranes, however, have demonstrated that the... |
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Visualizing myosin-actin interaction with a genetically-encoded fluorescent strain sensor.
Proc. Natl. Acad. Sci. U. S. A. 105(44) , 16882-7, (2008) Many proteins have been shown to undergo conformational changes in response to externally applied force in vitro, but whether the force-induced protein conformational changes occur in vivo remains unclear. To reveal the force-induced conformational changes, o... |
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Myoconductive and osteoinductive free-standing polysaccharide membranes.
Acta Biomater. 15 , 139-49, (2015) Free-standing (FS) membranes have increasing applications in the biomedical field as drug delivery systems for wound healing and tissue engineering. Here, we studied the potential of free-standing membranes made by the layer-by-layer assembly of chitosan and ... |
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4-hydroxybenzyl alcohol: a novel inhibitor of tumor angiogenesis and growth.
Life Sci. 93(1) , 44-50, (2013) The herbal compound 4-hydroxybenzyl alcohol (HBA) is a pleiotropic agent, which has been shown to effectively inhibit the development of new blood vessels by targeting multiple mechanisms of the angiogenic process. Because angiogenesis is a major prerequisite... |
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Dynamics of F-actin prefigure the structure of butterfly wing scales.
Dev. Biol. 392(2) , 404-18, (2014) The wings of butterflies and moths consist of dorsal and ventral epidermal surfaces that give rise to overlapping layers of scales and hairs (Lepidoptera, "scale wing"). Wing scales (average length ~200 µm) are homologous to insect bristles (macrochaetes), an... |
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Depolymerization of actin facilitates memory formation in an insect.
Biol. Lett. 8(6) , 1023-7, (2012) In mammals, memory formation and stabilization requires polymerization of actin. Here, we show that, in the honeybee, inhibition of actin polymerization within the brain centres involved in memory formation, the mushroom bodies (MBs), enhances associative olf... |
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The reorganization of actin filaments is required for vacuolar fusion of guard cells during stomatal opening in Arabidopsis.
Plant Cell Environ. 36(2) , 484-97, (2013) The reorganization of actin filaments (AFs) and vacuoles in guard cells is involved in the regulation of stomatal movement. However, it remains unclear whether there is any interaction between the reorganization of AFs and vacuolar changes during stomatal mov... |
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Independent migration of cell populations in the early gastrulation of the amphipod crustacean Parhyale hawaiensis.
Dev. Biol. 371(1) , 94-109, (2012) Cells are the principal component of tissues and can drive morphogenesis through dynamic changes in structure and interaction. During gastrulation, the primary morphogenetic event of early development, cells change shape, exchange neighbors, and migrate long ... |
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Extensive crosstalk between O-GlcNAcylation and phosphorylation regulates cytokinesis.
Sci. Signal. 3 , ra2, (2010) Like phosphorylation, the addition of O-linked beta-N-acetylglucosamine (O-GlcNAcylation) is a ubiquitous, reversible process that modifies serine and threonine residues on nuclear and cytoplasmic proteins. Overexpression of the enzyme that adds O-GlcNAc to t... |