sulfisomidine

sulfisomidine Structure
sulfisomidine structure
Common Name sulfisomidine
CAS Number 515-64-0 Molecular Weight 278.330
Density 1.4±0.1 g/cm3 Boiling Point 480.7±55.0 °C at 760 mmHg
Molecular Formula C12H14N4O2S Melting Point 245ºC
MSDS Chinese USA Flash Point 244.5±31.5 °C
Symbol GHS07
GHS07
Signal Word Warning

Fast determination of 22 sulfonamides from chicken breast muscle using core-shell nanoring amino-functionalized superparamagnetic molecularly imprinted polymer followed by liquid chromatography-tandem mass spectrometry.

J. Chromatogr. A. 1345 , 17-28, (2014)

A novel, simple and sensitive method was developed for the simultaneous determination of 22 sulfonamides (SAs) in chicken breast muscle by using the dispersive micro-solid-phase extraction (d-μ-SPE) procedure combined with ultra-fast liquid chromatography-tan...

Multiresidue analysis of sulfonamides, quinolones, and tetracyclines in animal tissues by ultra-high performance liquid chromatography-tandem mass spectrometry.

Food Chem. 204 , 252-62, (2016)

A multiresidue method for the efficient identification and quantification of 38 compounds from 3 different classes of antibiotics (tetracyclines, sulfonamides, and quinolones) in animal tissues has been developed. The method optimization involved the selectio...

Coulometric determination of sulphisomidine, sulphamethoxydiazine and sulphamoxole.

J. Pharm. Biomed. Anal. 9(2) , 199-201, (1991)

Identification of the 'wrong' active pharmaceutical ingredient in a counterfeit Halfan drug product using accurate mass electrospray ionisation mass spectrometry, accurate mass tandem mass spectrometry and liquid chromatography/mass spectrometry.

Rapid Commun. Mass Spectrom. 17(3) , 215-21, (2003)

Methodology is presented for identifying an unknown active (pharmaceutical) ingredient (AI) in a counterfeit drug product. A range of mass spectrometric techniques, i.e., accurate mass mass spectrometry, tandem mass spectrometry (MS/MS) and liquid chromatogra...

Lack of oxidative pathways in the metabolism of sulphisomidine by the turtle Pseudemys scripta elegans.

J. Vet. Pharmacol. Ther. 12(4) , 459-62, (1989)

Extended Hildebrand solubility approach: solubility of tolbutamide, acetohexamide, and sulfisomidine in binary solvent mixtures.

J. Pharm. Sci. 71(4) , 439-42, (1982)

The extended Hildebrand approach for predicting solubilities of crystalline compounds in solvent mixtures was tested using tolbutamide, acetohexamide, and sulfisomidine in mixed solvents consisting of hexane-absolute ethanol and 95% (v/v) ethyl alcohol-aqueou...

Direct drug transport from the rat nasal cavity to the cerebrospinal fluid: the relation to the dissociation of the drug.

J. Pharm. Pharmacol. 46(5) , 378-9, (1994)

We aimed to clarify the relationship between drug dissociation (sulphisomidine) and its direct transport from the nasal cavity to the cerebrospinal fluid (CSF). Rat nasal cavities were perfused in a single pass system with buffers (pH 5.5, 6.5, 7.4, 8.7 and 9...

Effect of different sulfonamides on the human serum complement system.

Int. Arch. Allergy Appl. Immunol. 76(3) , 205-13, (1985)

Incubation of normal human serum with different sulfonamides led to a dose-dependent inactivation of total hemolytic complement activity. A decrease of the activities of C1, C2, C3, C5 and one or several of the components C6-9 was observed after treatment of ...

Renal tubular excretion of the N4-acetyl metabolites of sulphasomidine and sulphadimethoxine in the dog.

J. Pharm. Pharmacol. 45(7) , 614-7, (1993)

To investigate whether dogs are able to excrete acetylated drugs by active transport, the plasma kinetics and renal excretion of the N4-acetyl metabolites of sulphasomidine and sulphadimethoxine were studied in the beagle dog after a rapid intravenous bolus i...

Antibiotic susceptibility pattern and capsular types of Haemophilus influenzae recovered from clinical specimens in northern Norway.

Acta Pathol. Microbiol. Immunol. Scand. B. 91(6) , 383-7, (1983)

One hundred and nine strains of Haemophilus influenzae recovered from clinical specimens were examined for antibiotic sensitivity pattern and capsular types. All strains from blood cultures, cerebrospinal fluid and a joint aspirate were type b whereas most of...