sulfisomidine

Modify Date: 2025-08-25 18:42:22

sulfisomidine Structure
sulfisomidine structure
Common Name sulfisomidine
CAS Number 515-64-0 Molecular Weight 278.330
Density 1.4±0.1 g/cm3 Boiling Point 480.7±55.0 °C at 760 mmHg
Molecular Formula C12H14N4O2S Melting Point 245ºC
MSDS Chinese USA Flash Point 244.5±31.5 °C
Symbol GHS07
GHS07
Signal Word Warning

 Use of sulfisomidine


Sulfisomidin is a sulfonamide antibacterial.

 Names

Name sulfisomidine
Synonym More Synonyms

 sulfisomidine Biological Activity

Description Sulfisomidin is a sulfonamide antibacterial.
Related Catalog
In Vitro Sulfisomidin (Sulfaisodimidine) is a short-acting antibacterial agent[1].
References

[1]. Bridges JW, et al. Species differences in the metabolism and excretion of sulphasomidine andsulphamethomidine. Biochem J. 1969 Jan;111(2):173-9.

 Chemical & Physical Properties

Density 1.4±0.1 g/cm3
Boiling Point 480.7±55.0 °C at 760 mmHg
Melting Point 245ºC
Molecular Formula C12H14N4O2S
Molecular Weight 278.330
Flash Point 244.5±31.5 °C
Exact Mass 278.083740
PSA 106.35000
LogP -0.43
Vapour Pressure 0.0±1.2 mmHg at 25°C
Index of Refraction 1.644
Storage condition 0-6°C

 Toxicological Information

CHEMICAL IDENTIFICATION

RTECS NUMBER :
WO9270000
CHEMICAL NAME :
Sulfanilamide, N(sup 1)-(2,6-dimethyl-4-pyrimidinyl)-
CAS REGISTRY NUMBER :
515-64-0
BEILSTEIN REFERENCE NO. :
0261305
LAST UPDATED :
199707
DATA ITEMS CITED :
3
MOLECULAR FORMULA :
C12-H14-N4-O2-S
MOLECULAR WEIGHT :
278.36
WISWESSER LINE NOTATION :
T6N CNJ B1 D1 FMSWR DZ

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Oral
SPECIES OBSERVED :
Rodent - mouse
DOSE/DURATION :
50 gm/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
REFERENCE :
AIPTAK Archives Internationales de Pharmacodynamie et de Therapie. (Heymans Institute of Pharmacology, De Pintelaan 185, B-9000 Ghent, Belgium) V.4- 1898- Volume(issue)/page/year: 94,338,1953 ** REPRODUCTIVE DATA **
TYPE OF TEST :
TDLo - Lowest published toxic dose
ROUTE OF EXPOSURE :
Oral
DOSE :
6 gm/kg
SEX/DURATION :
female 9-14 day(s) after conception
TOXIC EFFECTS :
Reproductive - Fertility - post-implantation mortality (e.g. dead and/or resorbed implants per total number of implants)
REFERENCE :
SEIJBO Senten Ijo. Congenital Anomalies. (Nippon Senten Ijo Gakkai, c/o Kinki Daigaku Igakubu Kaibagaku Kyoshitsu, 380 Nishiyama, Sayama-cho, Mirami-Kawachi-gun, Osaka-fu, Japan) V.1-26, 1960-86. For publisher information, see CGANE7. Volume(issue)/page/year: 13,7,1973
TYPE OF TEST :
TDLo - Lowest published toxic dose
ROUTE OF EXPOSURE :
Unreported
DOSE :
2500 mg/kg
SEX/DURATION :
female 8-12 day(s) after conception
TOXIC EFFECTS :
Reproductive - Fertility - post-implantation mortality (e.g. dead and/or resorbed implants per total number of implants)
REFERENCE :
AKGIAO Akushcherstvo i Ginekologiya (Moscow). (V/O Mezhdunarodnaya Kniga, 113095 Moscow, USSR) No.1- 1936- Volume(issue)/page/year: 43(12),10,1967

 Safety Information

Symbol GHS07
GHS07
Signal Word Warning
Hazard Statements H315-H319-H335
Precautionary Statements P261-P305 + P351 + P338
Personal Protective Equipment dust mask type N95 (US);Eyeshields;Gloves
Hazard Codes Xi
Risk Phrases 36/37/38
Safety Phrases S26;S36
RIDADR UN 3249
RTECS WO9270000
Packaging Group III
Hazard Class 6.1(b)
HS Code 2935009090

 Synthetic Route

 Customs

HS Code 2935009090
Summary 2935009090 other sulphonamides VAT:17.0% Tax rebate rate:9.0% Supervision conditions:none MFN tariff:6.5% General tariff:35.0%

 Articles27

More Articles
Fast determination of 22 sulfonamides from chicken breast muscle using core-shell nanoring amino-functionalized superparamagnetic molecularly imprinted polymer followed by liquid chromatography-tandem mass spectrometry.

J. Chromatogr. A. 1345 , 17-28, (2014)

A novel, simple and sensitive method was developed for the simultaneous determination of 22 sulfonamides (SAs) in chicken breast muscle by using the dispersive micro-solid-phase extraction (d-μ-SPE) p...

Multiresidue analysis of sulfonamides, quinolones, and tetracyclines in animal tissues by ultra-high performance liquid chromatography-tandem mass spectrometry.

Food Chem. 204 , 252-62, (2016)

A multiresidue method for the efficient identification and quantification of 38 compounds from 3 different classes of antibiotics (tetracyclines, sulfonamides, and quinolones) in animal tissues has be...

Coulometric determination of sulphisomidine, sulphamethoxydiazine and sulphamoxole.

J. Pharm. Biomed. Anal. 9(2) , 199-201, (1991)

 Synonyms

Solfisomidina
4-amino-N-(2,6-dimethyl-pyrimidin-4-yl)-benzenesulfonamide
Sulfaisodimidinum
4-amino-N-(2,6-dimethyl-4-pyrimidinyl)benzenesulfonamide
Sulfaisodimidine
Sulfisomidin
Sulfaisomidine
6-(Sulfanilamido)-2,4-dimethyl-1,3-diazine
sulfisomidine
Sulfadimetine
benzenesulfonamide, 4-amino-N-(2,6-dimethyl-4-pyrimidinyl)-
Sulfuisodimidine
Sulphasomidine
Sulfasomidine
MFCD00010567
4-Amino-N-(2,6-dimethylpyrimidin-4-yl)benzenesulfonamide
Sulfudimetine
EINECS 208-204-3
Sulfamethin
2,6-dimethyl-4-pyrimidinyl sulphanilamide
6-(p-Aminophenylsulfonamido)-2,4-dimethylpyrimidine
Domain
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