19-hydroxy-8(17),13-labdadien-16,15-olide

19-hydroxy-8(17),13-labdadien-16,15-olide Structure
19-hydroxy-8(17),13-labdadien-16,15-olide structure
Common Name 19-hydroxy-8(17),13-labdadien-16,15-olide
CAS Number 82209-74-3 Molecular Weight 318.45000
Density 1.09 Boiling Point N/A
Molecular Formula C20H30O3 Melting Point 106-107ºC
MSDS Chinese USA Flash Point N/A

Andrograpanin, isolated from Andrographis paniculata, exhibits anti-inflammatory property in lipopolysaccharide-induced macrophage cells through down-regulating the p38 MAPKs signaling pathways.

Int. Immunopharmacol. 8(7) , 951-8, (2008)

Andrographis paniculata Nees is an official herbal medicine for treatment of infection and inflammation in China. Andrograpanin, the one of diterpene lactones in A. paniculata, is a hydrolysate from neoandrographolide in vivo and in vitro. The goal of the pre...

Andrograpanin, a compound isolated from anti-inflammatory traditional Chinese medicine Andrographis paniculata, enhances chemokine SDF-1alpha-induced leukocytes chemotaxis.

J. Cell. Biochem. 95(5) , 970-8, (2005)

Andrographis paniculata is a traditional Chinese medicine (TCM) that has been effectively used for treatment of infection, inflammation, cold, fever, and diarrhea in China. However, mechanism of its therapeutic function is not well known. In the current study...