82209-74-3
82209-74-3 structure
- Name: 19-hydroxy-8(17),13-labdadien-16,15-olide
- Chemical Name: 4-[2-[(1R,4aS,5R,8aS)-5-(hydroxymethyl)-5,8a-dimethyl-2-methylidene-3,4,4a,6,7,8-hexahydro-1H-naphthalen-1-yl]ethyl]-2H-furan-5-one
- CAS Number: 82209-74-3
- Molecular Formula: C20H30O3
- Molecular Weight: 318.45000
- Catalog: analytical chemistry Standard Analytical standard
- Create Date: 2018-08-06 11:21:21
- Modify Date: 2024-01-05 22:04:03
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Andrograpanin, a bioactive compound from Andrographis paniculata, exhibits anti-inflammatory and anti-infectious properties[1][2].
| Name | 4-[2-[(1R,4aS,5R,8aS)-5-(hydroxymethyl)-5,8a-dimethyl-2-methylidene-3,4,4a,6,7,8-hexahydro-1H-naphthalen-1-yl]ethyl]-2H-furan-5-one |
|---|---|
| Synonyms |
2(5H)-Furanone,3-(2-((1R,4aS,5R,8aS)-decahydro-5-(hydroxymethyl)-5,8a-dimethyl-2-methylene-1-naphthalenyl)ethyl)
UNII-89M92UDM18 3,14-Dideoxyandrographolide 19-hydroxy-8(17),13-ent-labdadien-15->16 lactone andrograpanin |
| Description | Andrograpanin, a bioactive compound from Andrographis paniculata, exhibits anti-inflammatory and anti-infectious properties[1][2]. |
|---|---|
| Related Catalog | |
| In Vitro | Andrograpanin exhibits anti-inflammatory properties in lipopolysaccharide-induced macrophage cells through down-regulating the p38 MAPKs signaling pathways[1]. Andrograpanin enhances chemokine SDF-1α-induced leukocytes chemotaxis in Jurkat, THP-1 and PBL cells[2]. |
| References |
| Density | 1.09 |
|---|---|
| Melting Point | 106-107ºC |
| Molecular Formula | C20H30O3 |
| Molecular Weight | 318.45000 |
| Exact Mass | 318.21900 |
| PSA | 46.53000 |
| LogP | 4.02100 |
| Hazard Codes | Xi |
|---|---|
| RIDADR | NONH for all modes of transport |
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82209-74-3 |
| Literature: Fujita, Tetsuro; Fujitani, Ryujiro; Takeda, Yoshio; Takaishi, Yoshihisa; Yamada, Toshihide; et al Chemical & Pharmaceutical Bulletin, 1984 , vol. 32, # 6 p. 2117 - 2125 |
