Luteolin
Luteolin structure
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Common Name | Luteolin | ||
|---|---|---|---|---|
| CAS Number | 491-70-3 | Molecular Weight | 286.236 | |
| Density | 1.7±0.1 g/cm3 | Boiling Point | 616.1±55.0 °C at 760 mmHg | |
| Molecular Formula | C15H10O6 | Melting Point | ~330 °C(lit.) | |
| MSDS | Chinese USA | Flash Point | 239.5±25.0 °C | |
| Symbol |
GHS07 |
Signal Word | Warning | |
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A Food-Derived Flavonoid Luteolin Protects against Angiotensin II-Induced Cardiac Remodeling.
PLoS ONE 10 , e0137106, (2015) Oxidative stress has been implicated in cardiac remodeling (cardiac fibrosis and hypertrophy), which impairs cardiac function and metabolism; therefore, it is anticipated antioxidative compounds will have protective properties against cardiac remodeling. Lute... |
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Sesquiterpenes with TRAIL-resistance overcoming activity from Xanthium strumarium.
Bioorg. Med. Chem. 23 , 4746-54, (2015) The ability of TRAIL to selectively induce apoptosis in cancer cells while sparing normal cells makes it an attractive target for the development of new cancer therapy. In search of bioactive natural products for overcoming TRAIL-resistance from natural resou... |
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Metabolite profiling of polyphenols in the Tunisian plant Tamarix aphylla (L.) Karst.
J. Pharm. Biomed. Anal. 99 , 97-105, (2014) In this study, a detailed investigation on the composition of polyphenols of Tamarix aphylla (L.) Karst., consisting of phenolic acids and flavonoids, was carried out. In order to optimize the yield of secondary metabolites, three extraction techniques were c... |
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Luteolin arrests cell cycling, induces apoptosis and inhibits the JAK/STAT3 pathway in human cholangiocarcinoma cells.
Asian Pac. J. Cancer Prev. 15(12) , 5071-6, (2014) Cholangiocarcinoma (CCA) is one of the aggressive cancers with a very poor prognosis. Several efforts have been made to identify and develop new agents for prevention and treatment of this deadly disease. In the present study, we examined the anticancer effec... |
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Binding and Anticancer Properties of Plumbagin with Human Serum Albumin.
Chem. Biol. Drug Des. 86 , 362-9, (2015) Plumbagin has received extensive attention as a promising anticancer drug. Therefore, we investigated the binding and anticancer properties of plumbagin with human serum albumin. Fluorescence results demonstrated that plumbagin interacts with human serum albu... |
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Differential metabolomic analysis of the potential antiproliferative mechanism of olive leaf extract on the JIMT-1 breast cancer cell line.
J. Pharm. Biomed. Anal. 105 , 156-62, (2015) A new differential metabolomic approach has been developed to identify the phenolic cellular metabolites derived from breast cancer cells treated with a supercritical fluid extracted (SFE) olive leaf extract. The SFE extract was previously shown to have signi... |
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Activity-guided isolation, identification and quantification of biologically active isomeric compounds from folk medicinal plant Desmodium adscendens using high performance liquid chromatography with diode array detector, mass spectrometry and multidimentional nuclear magnetic resonance spectroscopy.
J. Pharm. Biomed. Anal. 102 , 54-63, (2014) The antioxidant activity of the crude extract (60% ethanol) from the leaves of Desmodium adscendens (Sw.) DC. (Fabaceae) was observed in DPPH, xanthine/xanthine oxidase, lipid peroxydation and neutrophils burst tests. Further activity-guided fractionation on ... |
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Chemical genetics reveals a complex functional ground state of neural stem cells.
Nat. Chem. Biol. 3(5) , 268-273, (2007) The identification of self-renewing and multipotent neural stem cells (NSCs) in the mammalian brain holds promise for the treatment of neurological diseases and has yielded new insight into brain cancer. However, the complete repertoire of signaling pathways ... |
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New Polyphenols Identified in Artemisiae abrotani herba Extract.
Molecules 20 , 11063-75, (2015) Artemisia abrotanum L. ("southernwood") belongs to the Artemisia genus and it is used in traditional medicine for the treatment of a variety of illnesses. Scarce data is available on the chemical composition of this medicinal plant, most research being focuse... |
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Comparative Studies on Polyphenolic Composition, Antioxidant and Diuretic Effects of Nigella sativa L. (Black Cumin) and Nigella damascena L. (Lady-in-a-Mist) Seeds.
Molecules 20 , 9560-74, (2015) This study was performed to evaluate the phenolic profile, antioxidant and diuretic effects of black cumin and lady-in-a-mist seeds. In the phenolic profile, differences between the two species are significant. Qualitative and quantitative analyses of the phe... |