Phenformin (hydrochloride)
Phenformin (hydrochloride) structure
|
Common Name | Phenformin (hydrochloride) | ||
|---|---|---|---|---|
| CAS Number | 834-28-6 | Molecular Weight | 241.721 | |
| Density | 1.24 g/cm3 | Boiling Point | 413.7ºC at 760 mmHg | |
| Molecular Formula | C10H16ClN5 | Melting Point | 175-178ºC | |
| MSDS | Chinese USA | Flash Point | 204ºC | |
| Symbol |
GHS07 |
Signal Word | Warning | |
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Hydrogen sulfide mitigates hyperglycemic remodeling via liver kinase B1-adenosine monophosphate-activated protein kinase signaling.
Biochim. Biophys. Acta 1843(12) , 2816-26, (2014) Hyperglycemia (HG) reduces AMPK activation leading to impaired autophagy and matrix accumulation. Hydrogen sulfide (H2S) treatment improves HG-induced renovascular remodeling however, its mechanism remains unclear. Activation of LKB1 by the formation of heter... |
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Lactic acidosis treatment by nanomole level of spermidine in an animal model.
Regul Toxicol Pharmacol 70(2) , 514-8, (2014) Lactic acidosis occurs in a number of clinical conditions, e.g. in surgeries, orthotopic liver transplant, and anesthetic agent administration, which has deleterious effects on the patient's survival. The most rational therapy for these patients, the sodium b... |
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