Sulbactam
Sulbactam structure
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Common Name | Sulbactam | ||
|---|---|---|---|---|
| CAS Number | 68373-14-8 | Molecular Weight | 233.242 | |
| Density | 1.6±0.1 g/cm3 | Boiling Point | 567.7±50.0 °C at 760 mmHg | |
| Molecular Formula | C8H11NO5S | Melting Point | 146-151ºC | |
| MSDS | Chinese USA | Flash Point | 297.1±30.1 °C | |
| Symbol |
GHS07 |
Signal Word | Warning | |
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Molecular mechanisms of sulbactam antibacterial activity and resistance determinants in Acinetobacter baumannii.
Antimicrob. Agents Chemother. 59(3) , 1680-9, (2015) Sulbactam is a class A β-lactamase inhibitor with intrinsic whole-cell activity against certain bacterial species, including Acinetobacter baumannii. The clinical use of sulbactam for A. baumannii infections is of interest due to increasing multidrug resistan... |
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The spread of bla OXA-48 and bla OXA-244 carbapenemase genes among Klebsiella pneumoniae, Proteus mirabilis and Enterobacter spp. isolated in Moscow, Russia.
Ann. Clin. Microbiol. Antimicrob. 14 , 46, (2015) The spread of carbapenemase-producing Enterobacteriaceae (CPE) is a great problem of healthcare worldwide. Study of the spread for bla OXA-48-like genes coding epidemically significant carbapenemases among hospital pathogens is important for the regional and ... |
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Investigation of a possible outbreak of carbapenem-resistant Acinetobacter baumannii in Odense, Denmark using PFGE, MLST and whole-genome-based SNPs.
J. Antimicrob. Chemother. 70 , 1965-8, (2015) The objectives were to study a possible outbreak of carbapenem-resistant Acinetobacter baumannii by comparing three different typing methods (PFGE, MLST and whole-genome SNPs) and to compare the resistance gene profiles of the isolates.From December 2012 to O... |
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Clinical correlation between HBV infection and concomitant bacterial infections.
Sci. Rep. 5 , 15413, (2015) Bacterial infections are common in patients suffering viral hepatitis and critical for prognosis. However, any correlation between HBV and concomitant bacterial infections is not well characterized. A retrospective study was conducted from Jan 2012 to Jan 201... |
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Antibiotic-modifying activity of riachin, a non-cyanogenic cyanoglycoside extracted from Bauhinia pentandra.
Drug Des. Devel. Ther. 9 , 3067-72, (2015) The search for new active compounds from the Brazilian flora has intensified in recent years, especially for new drugs with antibiotic potential. Accordingly, the aim of this study was to determine whether riachin has antibiotic activity in itself or is able ... |
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Randomized comparison of piperacillin-tazobactam plus amikacin versus cefoperazone-sulbactam plus amikacin for management of febrile neutropenia in children with lymphoma and solid tumors.
Pediatr. Hematol. Oncol. 30(2) , 141-8, (2013) The objective of this study was to compare the effectiveness of piperacillin-tazobactam (PIP/TAZO) plus amikacin (AMK) (PIP/TAZO+AMK) versus cefoperazone-sulbactam (CS) plus AMK (CS+AMK) for the treatment of febrile neutropenia (FN) in children with cancer. T... |
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Dissemination of blaOXA-23 in Acinetobacter spp. in China: main roles of conjugative plasmid pAZJ221 and transposon Tn2009.
Antimicrob. Agents Chemother. 59 , 1998-2005, (2015) Production of the OXA-23 carbapenemase is the most common reason for the increasing carbapenem resistance in Acinetobacter spp. This study was conducted to reveal the genetic basis of blaOXA-23 dissemination in Acinetobacter spp. in China. A total of 63 carba... |
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Antibiotic regimens for management of intra-amniotic infection.
Cochrane Database Syst. Rev. 12 , CD010976, (2014) Chorioamnionitis is a common infection that affects both mother and infant. Infant complications associated with chorioamnionitis include early neonatal sepsis, pneumonia, and meningitis. Chorioamnionitis can also result in maternal morbidity such as pelvic i... |
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Anaerobiospirillum succiniciproducens-induced bacteremia in a healthy man.
Am. J. Emerg. Med. 32(7) , 812.e1-3, (2014) Anaerobiospirillum succiniciproducens is rarely associated with bacteremia but results in significant mortality. Almost all reported bacteremia cases have occurred in immunocompromised hosts, such as those with alcoholic liver disease, atherosclerosis, recent... |
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In vitro pharmacodynamics of human-simulated exposures of ampicillin/sulbactam, doripenem and tigecycline alone and in combination against multidrug-resistant Acinetobacter baumannii.
J. Antimicrob. Chemother. 68(10) , 2296-304, (2013) Multidrug resistance is common among Acinetobacter baumannii, limiting the available options used to treat infections caused by this organism. The objective of this study was to compare monotherapy and combination therapy with ampicillin/sulbactam, doripenem ... |