β-1,3-Glucan

β-1,3-Glucan Structure
β-1,3-Glucan structure
Common Name β-1,3-Glucan
CAS Number 9051-97-2 Molecular Weight 486.42200
Density N/A Boiling Point N/A
Molecular Formula C18H30O15 Melting Point N/A
MSDS USA Flash Point N/A

How carbohydrates sculpt cells: chemical control of morphogenesis in the yeast cell wall.

Nat. Rev. Microbiol. 11(9) , 648-55, (2013)

In budding yeast, the neck that connects the mother and daughter cell is the site of essential functions such as organelle trafficking, septum formation and cytokinesis. Therefore, the morphology of this region, which depends on the surrounding cell wall, mus...

An initial event in the insect innate immune response: structural and biological studies of interactions between β-1,3-glucan and the N-terminal domain of β-1,3-glucan recognition protein.

Biochemistry 52(1) , 161-70, (2013)

In response to invading microorganisms, insect β-1,3-glucan recognition protein (βGRP), a soluble receptor in the hemolymph, binds to the surfaces of bacteria and fungi and activates serine protease cascades that promote destruction of pathogens by means of m...

Interleukin-23 mediates the intestinal response to microbial β-1,3-glucan and the development of spondyloarthritis pathology in SKG mice.

Arthritis Rheumatology 66(7) , 1755-67, (2014)

Spondyloarthritides (SpA) occur in 1% of the population and include ankylosing spondylitis (AS) and arthropathy of inflammatory bowel disease (IBD), with characteristic spondylitis, arthritis, enthesitis, and IBD. Genetic studies implicate interleukin-23 (IL-...

Extracellular cell wall β(1,3)glucan is required to couple septation to actomyosin ring contraction.

J. Cell Biol. 203(2) , 265-82, (2013)

Cytokinesis has been extensively studied in different models, but the role of the extracellular cell wall is less understood. Here we studied this process in fission yeast. The essential protein Bgs4 synthesizes the main cell wall β(1,3)glucan. We show that B...

Soluble β-1,3/1,6-glucan in seaweed from the southern hemisphere and its immunomodulatory effect.

Carbohydr. Polym. 92(1) , 241-8, (2013)

Five types of macroalgae from the southern hemisphere were analysed for the presence of β-1,3/1,6-glucan and its immunostimulant properties. We were able to extract soluble β-1,3/1,6-D-glucan from Durvillaea antarctica (Chamisso) Hariot (DA). The morphology o...

Evidence for a novel biological role for the multifunctional β-1,3-glucan binding protein in shrimp

Mol. Immunol. 51(3-4) , 363-7, (2012)

Highlights ► Purified Farfantepenaeus paulensis (FpβGBP) and Litopenaeus schmitti (LsβGBP) βGBPs were able to enhance the activation of the proPO system. ► Shrimp βGBPs are able to agglutinate fungal cells, in a lectin-like manner. ► This is the first evidenc...

Development and application of mold antigen-specific enzyme-linked immunosorbent assays (ELISA) to quantify airborne antigen exposure.

J. Toxicol. Environ. Health A 75(19-20) , 1185-93, (2012)

The aim of our study was to develop specific enzyme-linked immunosorbent assays (ELISAs) and apply these to assess mold antigen exposure in composting plants. Sandwich ELISAs based on polyclonal antibodies to Aspergillus fumigatus (Af), Penicillium chrysogenu...

β(1,3)-glucan synthase complex from Alternaria infectoria, a rare dematiaceous human pathogen.

Med. Mycol 50(7) , 716-25, (2012)

The fungal cell wall polymer β-(1,3)-D-glucan is synthesized by the enzyme β-(1,3)- D-glucan synthase that is a complex composed of at least two proteins, Rho1p and Fks1p. Here, we report the nucleotide sequence of a single FKS gene and of the regulatory unit...

Structural characterization and antioxidative activity of low-molecular-weights beta-1,3-glucan from the residue of extracted Ganoderma lucidum fruiting bodies.

J. Biomed. Biotechnol. 2012 , 673764, (2012)

The major cell wall constituent of Ganoderma lucidum (G. lucidum) is β-1,3-glucan. This study examined the polysaccharide from the residues of alkaline-extracted fruiting bodies using high-performance anion-exchange chromatography (HPAEC), and it employed nuc...

Evaluation of plasma (1-->3) beta-D-glucan concentrations in birds naturally and experimentally infected with aspergillus fumigatus.

Avian Dis. 56(1) , 183-91, (2012)

Avian aspergillosis, most often caused by Aspergillus fumigatus, is a common and devastating disease affecting a range of bird species. Early diagnosis is difficult and often unreliable. The current study evaluated the utility of measuring (1-->3)-beta-D-gluc...