Molecular Immunology 2012-07-01

Evidence for a novel biological role for the multifunctional β-1,3-glucan binding protein in shrimp

Priscila Goncalves, Javier Vernal, Rafael Diego Rosa, Gloria Yepiz-Plascencia, Claudia Regina Batista de Souza, Margherita Anna Barracco, Luciane Maria Perazzolo

Index: Mol. Immunol. 51(3-4) , 363-7, (2012)

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Abstract

Highlights ► Purified Farfantepenaeus paulensis (FpβGBP) and Litopenaeus schmitti (LsβGBP) βGBPs were able to enhance the activation of the proPO system. ► Shrimp βGBPs are able to agglutinate fungal cells, in a lectin-like manner. ► This is the first evidence of a lectin-like activity for βGBP. ► FpβGBP showed to be constitutively expressed and was not modulated by a non-lethal dose of filamentous fungi.