Methyl 4-bromo-2-chloronicotinate

Methyl 4-bromo-2-chloronicotinate Structure
Methyl 4-bromo-2-chloronicotinate structure
Common Name Methyl 4-bromo-2-chloronicotinate
CAS Number 1064678-14-3 Molecular Weight 250.47700
Density N/A Boiling Point N/A
Molecular Formula C7H5BrClNO2 Melting Point 54-58°C
MSDS Chinese USA Flash Point >230 °F
Symbol GHS09
GHS09
Signal Word Warning

Novel small molecule bradykinin B2 receptor antagonists.

J. Med. Chem. 14th ed., 52 , 4370-4379, (2009)

Blockade of the bradykinin B(2) receptor provides therapeutic benefit in hereditary angioedema (HAE) and potentially in many other diseases. Herein, we describe the development of highly potent B(2) receptor antagonists with a molecular weight of approximatel...