salvianolic acid B
salvianolic acid B structure
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Common Name | salvianolic acid B | ||
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| CAS Number | 121521-90-2 | Molecular Weight | 718.614 | |
| Density | 1.6±0.1 g/cm3 | Boiling Point | 1020.3±65.0 °C at 760 mmHg | |
| Molecular Formula | C36H30O16 | Melting Point | 98-110ºC | |
| MSDS | USA | Flash Point | 322.1±27.8 °C | |
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Surfactant-coated graphitized multiwalled carbon nanotubes as the pseudostationary phase in electrokinetic chromatography for the analysis of phytochemical compounds in biological fluids.
Electrophoresis 36(7-8) , 1055-63, (2015) This report describes the use of surfactant-coated graphitized multiwalled carbon nanotubes (SC-GMWNTs) as a novel pseudostationary phase in CE with diode array detection for the determination of phenolic acids and tanshinones in herbal and urine samples. Sev... |
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Tissue-smashing based ultra-rapid extraction of chemical constituents in herbal medicines
J. Pharm. Biomed. Anal. 95 , 213-9, (2014) Sample extraction is the first challenge in analysis of herbal medicines (HMs). Numerous methods have been developed to improve extraction efficiency, use less solvent and short time. In this work, a tissue-smashing based ultra-rapid extraction (TSURE) method... |
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The caffeic acid in aqueous extract of Tournefortia sarmentosa enhances neutrophil phagocytosis of Escherichia coli.
Immunopharmacol. Immunotoxicol. 36(6) , 390-6, (2014) Tournefortia sarmentosa, a Chinese herbal medicine, is considered an antioxidant or a detoxicating agent. Recently T. sarmentosa has received attention for its effects on the immune response. Here we provide evidence that aqueous extract of T. sarmentosa can ... |
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Overexpression of allene oxide cyclase promoted tanshinone/phenolic acid production in Salvia miltiorrhiza.
Plant Cell Rep. 31(12) , 2247-59, (2012) This study provides a desirable candidate gene resource (SmAOC) to increase the content of valuable natural products via appropriate JA pathway genetic engineering. Jasmonates (JAs) are important signal molecules in plants. They regulate transcripts of defens... |
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Design, synthesis, and discovery of stilbene derivatives based on lithospermic acid B as potent protein tyrosine phosphatase 1B inhibitors.
Bioorg. Med. Chem. Lett. 17 , 4481-6, (2007) Dihydroxy stilbene derivatives were designed based on lithospermic acid B and were prepared from 4-(chloromethyl)benzoic acid. The inhibitory activities of the novel compounds against protein tyrosine phosphatase 1B (PTP1B) were evaluated. 3,4-Dihydroxy stilb... |
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Hydrolytic kinetics of lithospermic acid B extracted from roots of Salvia miltiorrhiza.
J. Pharm. Biomed. Anal. 43(2) , 435-9, (2007) The hydrolytic kinetics of lithospermic acid B (LAB) extracted from the roots of Salvia miltiorrhiza (Chinese herb: danshen) was investigated by using reversed-phase high-performance liquid chromatography (HPLC) with UV-vis detection. The influences of initia... |
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Pharmacokinetics, tissue distribution, metabolism, and excretion of depside salts from Salvia miltiorrhiza in rats.
Drug Metab. Dispos. 35(2) , 234-9, (2007) Salviae miltiorrhiza, a traditional Chinese medical herb known as "Danshen," has been widely used in clinics to improve blood circulation, relieve blood stasis, and treat coronary heart disease. Depside salts from S. miltiorrhiza are a novel drug in which mag... |
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Lithospermic acid B isolated from Salvia miltiorrhiza ameliorates ischemia/reperfusion-induced renal injury in rats.
Life Sci. 75(15) , 1801-16, (2004) The present study was designed to examine whether lithospermic acid B (LSB) isolated from Salvia miltiorrhiza has an ameliorative effect on renal functional parameters in association with the expression of aquaporin 2 (AQP 2) and Na,K-ATPase in the ischemia-r... |
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Comparative study of seventeen Salvia plants: aldose reductase inhibitory activity of water and MeOH extracts and liquid chromatography-mass spectrometry (LC-MS) analysis of water extracts.
Chem. Pharm. Bull. 46(3) , 500-4, (1998) The dry root and rhizome of Salvia miltiorhiza (Lamiaceae) are used as a crude drug Danshen, while those of S. deserta (Xinjiang-Danshen) are mixed in Danshen at Xinjiang province when the former is in short supply. The water and MeOH extracts of S. deserta s... |
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Kinetics and mechanism of degradation of lithospermic acid B in aqueous solution.
J. Pharm. Biomed. Anal. 43(4) , 1249-55, (2007) The degradation of lithospermic acid B (LAB) was investigated as a function of buffer concentration, pH and temperature. Stability tests were performed using a stability-indicating high-performance liquid chromatography (HPLC) with UV-vis detection. The degra... |