(-)-JQ-1
(-)-JQ-1 structure
|
Common Name | (-)-JQ-1 | ||
|---|---|---|---|---|
| CAS Number | 1268524-71-5 | Molecular Weight | 456.988 | |
| Density | 1.3±0.1 g/cm3 | Boiling Point | 610.4±65.0 °C at 760 mmHg | |
| Molecular Formula | C23H25ClN4O2S | Melting Point | N/A | |
| MSDS | USA | Flash Point | 322.9±34.3 °C | |
|
Targeting bromodomains: epigenetic readers of lysine acetylation.
Nat. Rev. Drug Discov. 13(5) , 337-56, (2014) Lysine acetylation is a key mechanism that regulates chromatin structure; aberrant acetylation levels have been linked to the development of several diseases. Acetyl-lysine modifications create docking sites for bromodomains, which are small interaction modul... |
|
|
Epigenetic chemical probes. Müller S and Brown PJ
Clin. Pharmacol. Ther. 92(6) , 689-93, (2012)
|
|
|
Targeting chromatin readers. James LI and Frye SV
Clin. Pharmacol. Ther. 93(4) , 312-4, (2013)
|
Journals:
More...