8-Gingerol
8-Gingerol structure
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Common Name | 8-Gingerol | ||
|---|---|---|---|---|
| CAS Number | 23513-08-8 | Molecular Weight | 322.439 | |
| Density | 1.1±0.1 g/cm3 | Boiling Point | 476.4±35.0 °C at 760 mmHg | |
| Molecular Formula | C19H30O4 | Melting Point | 30 - 32 °C | |
| MSDS | Chinese USA | Flash Point | 162.6±19.4 °C | |
| Symbol |
GHS07 |
Signal Word | Warning | |
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Chemical profiling and quantification of Gua-Lou-Gui-Zhi decoction by high performance liquid chromatography/quadrupole-time-of-flight mass spectrometry and ultra-performance liquid chromatography/triple quadrupole mass spectrometry.
J. Chromatogr. B. Analyt. Technol. Biomed. Life Sci. 986-987 , 69-84, (2015) Gua-Lou-Gui-Zhi decoction (GLGZD) is a classical formula of traditional Chinese medicine, which has been commonly used to treat dysfunction after stroke, epilepsy and spinal cord injury. In this study, a systematic method was established for chemical profilin... |
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Regioselective glucuronidation of gingerols by human liver microsomes and expressed UDP-glucuronosyltransferase enzymes: reaction kinetics and activity correlation analyses for UGT1A9 and UGT2B7.
J. Pharm. Pharmacol. 67(4) , 583-96, (2015) To determine the reaction kinetics for regioselective glucuronidation of gingerols (i.e. 6-, 8- and 10-gingerol) by human liver microsomes and expressed UDP-glucuronosyltransferase (UGT) enzymes, and to identify the main UGT enzymes involved in regioselective... |
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Identification of serotonin 5-HT1A receptor partial agonists in ginger.
Bioorg. Med. Chem. 18 , 3345-51, (2010) Animal studies suggest that ginger (Zingiber officinale Roscoe) reduces anxiety. In this study, bioactivity-guided fractionation of a ginger extract identified nine compounds that interact with the human serotonin 5-HT(1A) receptor with significant to moderat... |
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Quantitation of 6-, 8- and 10-Gingerols and 6-Shogaol in Human Plasma by High-Performance Liquid Chromatography with Electrochemical Detection.
Int. J. Biomed. Sci. 6(3) , 233-240, (2010) Zingiber officinale is one of the most commonly used spices. We developed a method to determine the main pungent ginger constituents, 6-, 8- and 10-gingerols and 6-shogaol in human plasma. Quantitation was achieved using a reversed-phase C(18) column using hi... |
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Pharmacokinetics of 6-gingerol, 8-gingerol, 10-gingerol, and 6-shogaol and conjugate metabolites in healthy human subjects.
Cancer Epidemiol. Biomarkers Prev. 17(8) , 1930-6, (2008) Ginger shows promising anticancer properties. No research has examined the pharmacokinetics of the ginger constituents 6-gingerol, 8-gingerol, 10-gingerol, and 6-shogaol in humans. We conducted a clinical trial with 6-gingerol, 8-gingerol, 10-gingerol, and 6-... |
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High-performance liquid chromatography-electrospray mass spectrometric analysis of pungent constituents of ginger. He, Xian-guo, et al.
J. Chromatogr. A. 796.2 , 327-334, (1998)
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