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23513-08-8

23513-08-8 structure
23513-08-8 structure
  • Name: 8-Gingerol
  • Chemical Name: [8]-Gingerol
  • CAS Number: 23513-08-8
  • Molecular Formula: C19H30O4
  • Molecular Weight: 322.439
  • Catalog: Biochemical Chinese herbal medicine ingredients
  • Create Date: 2018-09-14 20:14:01
  • Modify Date: 2025-08-22 16:53:15
  • 8-Gingerol, found in the rhizomes of ginger (Z. officinale) with oral bioavailability, activates TRPV1, with an EC50 of 5.0 µM. 8-Gingerol inhibits COX-2, and inhibits the growth of H. pylori in vitro[1][2].

Name [8]-Gingerol
Synonyms 8-Gingerol
(S)-5-Hydroxy-1-(4-hydroxy-3-methoxyphenyl)-3-dodecanone
3-Dodecanone, 5-hydroxy-1-(4-hydroxy-3-methoxyphenyl)-, (5S)-
(5s)-5-hydroxy-1-(4-hydroxy-3-methoxyphenyl)dodecan-3-one
(5S)-5-Hydroxy-1-(4-hydroxy-3-methoxyphenyl)-3-dodecanone
Description 8-Gingerol, found in the rhizomes of ginger (Z. officinale) with oral bioavailability, activates TRPV1, with an EC50 of 5.0 µM. 8-Gingerol inhibits COX-2, and inhibits the growth of H. pylori in vitro[1][2].
Related Catalog
References

[1]. Dedov, V.N., et al. Gingerols: a novel class of vanilloid receptor (VR1) agonists. Br. J. Pharmacol. 137(6), 793-798 (2002).

[2]. Chrubasik, S., et al. Zingiberis rhizoma: A comprehensive review on the ginger effect and efficacy profiles. Phytomedicine 12(9), 684-701 (2005).

Density 1.1±0.1 g/cm3
Boiling Point 476.4±35.0 °C at 760 mmHg
Melting Point 30 - 32 °C
Molecular Formula C19H30O4
Molecular Weight 322.439
Flash Point 162.6±19.4 °C
Exact Mass 322.214417
PSA 66.76000
LogP 3.55
Vapour Pressure 0.0±1.3 mmHg at 25°C
Index of Refraction 1.517
Storage condition 2-8°C
Water Solubility methanol: soluble1mg/mL, clear, colorless

CHEMICAL IDENTIFICATION

RTECS NUMBER :
JR4362000
CHEMICAL NAME :
3-Dodecanone, 5-hydroxy-1-(4-hydroxy-3-methoxyphenyl)-, (S)-(+)-
CAS REGISTRY NUMBER :
23513-08-8
LAST UPDATED :
199503
DATA ITEMS CITED :
1
MOLECULAR FORMULA :
C19-H30-O4
MOLECULAR WEIGHT :
322.49

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Intraperitoneal
SPECIES OBSERVED :
Rodent - mouse
DOSE/DURATION :
>100 mg/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
REFERENCE :
ZYZAEU Zhongguo Yaoxue Zazhi. Chinese Pharmacuetical Journal. (China International Book Trading Corp., POB 2820, Beijing, Peop. China) V.24- 1989- Volume(issue)/page/year: 25,231,1990
Symbol GHS07
GHS07
Signal Word Warning
Hazard Statements H317
Precautionary Statements P280
Hazard Codes Xi: Irritant;
Risk Phrases 43
Safety Phrases 36/37
RIDADR NONH for all modes of transport
WGK Germany 3.0
RTECS JR4362000
HS Code 29145019
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