Triethylenetetramine

Triethylenetetramine Structure
Triethylenetetramine structure
Common Name Triethylenetetramine
CAS Number 112-24-3 Molecular Weight 146.234
Density 1.0±0.1 g/cm3 Boiling Point 266.5±0.0 °C at 760 mmHg
Molecular Formula C6H18N4 Melting Point 12 °C(lit.)
MSDS Chinese USA Flash Point 143.3±0.0 °C
Symbol GHS05 GHS07
GHS05, GHS07
Signal Word Danger

Synthesis and biological evaluation of a class of mitochondrially-targeted gadolinium(III) agents.

Chemistry 20(50) , 16602-12, (2014)

A structure-activity relationship study of a library of novel bifunctional Gd(III) complexes covalently linked to arylphosphonium cations is reported. Such complexes have been designed for potential application in binary cancer therapies such as neutron captu...

Chelating resin immobilizing carboxymethylated polyethyleneimine for selective solid-phase extraction of trace elements: Effect of the molecular weight of polyethyleneimine and its carboxymethylation rate.

Talanta 147 , 342-50, (2015)

The effect of the molecular weight of polyethyleneimine (PEI), defined as a compound having two or more ethyleneamine units, and of its carboxymethylation rate (CM/N), represented by the ratio of ion-exchange capacity to the amount of N on the resin, on the s...

Polyamines inhibit carbonic anhydrases by anchoring to the zinc-coordinated water molecule.

J. Med. Chem. 53 , 5511-22, (2010)

Carbonic anhydrases (CAs, EC 4.2.1.1) are inhibited by sulfonamides, phenols, and coumarins. Polyamines such as spermine, spermidine, and many synthetic congeners are described to constitute a novel class of CA inhibitors (CAIs), interacting with the differen...

The treatment of Wilson's disease, a rare genetic disorder of copper metabolism.

Sci. Prog. 96(Pt 1) , 19-32, (2013)

Wilson's disease is a rare autosomal recessive disease characterised by the deposition of copper in the brain, liver; cornea, and other organs. The overload of copper inevitably leads to progressive liver and neurological dysfunction. Copper overload in patie...

Synthesis of a carbon-dot-based photoluminescent probe for selective and ultrasensitive detection of Hg(2+) in water and living cells.

Analyst 140(4) , 1221-8, (2015)

A nitrogen and sulphur co-doped carbon dot (NSCD) based highly selective photoluminescent probe for mercury detection has been designed. The NSCDs with a PL quantum yield of 69% are easily prepared from a single polymeric molecular precursor. The turn on-off ...

Functional properties and biodistribution of poly(triethylenetetramine/cystamine bisacrylamide) and poly(triethylenetetramine/cystamine bisacrylamide)- poly(ethylene glycol) mixtures formed with nucleic acid.

J. Control. Release 159(1) , 111-9, (2012)

The clinical success of non-viral gene delivery reagents is hampered by their inefficient cellular transgene delivery, which is largely influenced by carrier properties that are currently undefined and misunderstood. In an attempt to further define and unders...

Rapid Screening of Immobilized Amine CO2 Sorbents for Steam Stability by Their Direct Contact with Liquid H2 O.

ChemSusChem 8 , 2041-5, (2015)

Rapid testing of hydrophilic and hydrophobic basic immobilized amine sorbents (BIAS) for CO2 capture stability under practical conditions was achieved by direct contact of the sorbents with flowing liquid water. Losses in both CO2 capture capacity and amine c...

Synthesis of homopolypeptides by aminolysis mediated by proteases encapsulated in silica nanospheres.

Macromol. Biosci. 14(11) , 1619-26, (2014)

We report the encapsulation of three different proteases in bioinspired silica. Silica particles were formed under mild reaction conditions using cationic amine-rich ethyleneamines as initiators, which resulted in aggregations of nanoscale spheres. Following ...

Comparative evaluation of small-molecule chemosensitizers in reversal of cisplatin resistance in ovarian cancer cells.

Anticancer Res. 32(9) , 3651-8, (2012)

Cisplatin-resistance is one of the major challenges in the treatment of epithelial ovarian cancer. Small-molecule chemosensitizers provide a therapeutically feasible approach to overcome cisplatin resistance in ovarian cancer. However, proper selection of che...

Optimization of poly(amido amine)s as vectors for siRNA delivery.

J. Control. Release 150(2) , 177-86, (2011)

By Michael addition polymerization of N,N'-cystaminebisacrylamide (CBA) with variable ratios of 4-amino-1-butanol (ABOL) and ethylene diamine (EDA) or triethylenetetramine (TETA), poly(amido amine) copolymers could be obtained with tunable charge densities. T...