Dithianon

Dithianon Structure
Dithianon structure
Common Name Dithianon
CAS Number 3347-22-6 Molecular Weight 296.324
Density 1.7±0.1 g/cm3 Boiling Point 402.1±45.0 °C at 760 mmHg
Molecular Formula C14H4N2O2S2 Melting Point 220ºC
MSDS Chinese USA Flash Point 197.0±28.7 °C
Symbol GHS07 GHS09
GHS07, GHS09
Signal Word Warning

Effect of thiol blocking agents on the binding of T3 and T4 in rat liver nuclear extract.

Acta Endocrinol. 98(1) , 68-72, (1981)

Liver nuclei bind thyroid hormones (T3 and T4) with different binding affinities. In out studies it was estimated that the apparent association constant (Ka) in the liver nuclei for T3 was 8.8 X 10(10) l mol-1 and for T4 was 4.1 X 10(9) l mol-1. We have found...

Identification of ABC transporter genes of Fusarium graminearum with roles in azole tolerance and/or virulence.

PLoS ONE 8 , e79042, (2013)

Fusarium graminearum is a plant pathogen infecting several important cereals, resulting in substantial yield losses and mycotoxin contamination of the grain. Triazole fungicides are used to control diseases caused by this fungus on a worldwide scale. Our prev...

In vitro cytotoxic and cell transforming activities exerted by the pesticides cyanazine, dithianon, diflubenzuron, procymidone, and vinclozolin on BALB/c 3T3 cells.

Environ. Mol. Mutagen. 21(1) , 81-6, (1993)

Cytotoxic and cell transforming activities of the pesticides cyanazine, diflubenzuron, dithianon, procymidone, and vinclozolin were investigated in vitro by utilizing the BALB/c 3T3 cell transformation test performed in the presence or in the absence of S-9 m...

Influence of the amendment of corn straw on the degradation behaviour of the fungicide dithianon in soil.

Environ. Pollut. 133(1) , 63-70, (2005)

Degradation studies were conducted with the fungicide (14)C-dithianon under standard conditions for 64 days in soil. The compound is characterized by mineralization losses of approx. 33% and the formation of non-extractable (bound) residues of approx. 63% in ...

Biomarkers of effect in evaluating dithianon cocarcinogenesis: selective induction and suppression of murine CYP3A isoform.

Cancer Lett. 113(1-2) , 221-8, (1997)

The ability of dithianon, whose mutagenic/cocarcinogenic activity has as yet not been clarified, to affect specific biomarkers of effect related to non-genotoxic cocarcinogenesis was investigated. For this purpose, several CYP-dependent reactions have been st...

Induction and suppression of murine CYP-mediated biotransformation by dithianon: organ- and sex-related differences.

Cancer Lett. 141(1-2) , 47-56, (1999)

With the aim of evaluating the co-carcinogenic properties of dithianon, the regio- and stereo-selective hydroxylation of testosterone was used as a multibiomarker of effect for cytochrome P450 (CYP) changes. CYP-catalysed reactions have been studied in liver,...

Structural and functional approach to studying pesticide side-effects on specific soil functions.

Environ. Toxicol. Chem. 22(4) , 784-90, (2003)

The microbial communities in the soil are responsible for material cycling and thus also for maintaining the fertility of agricultural soils. In order to assess pesticide side effects on the soil processes, detailed knowledge is required about the structure a...

Interactions between yeasts, fungicides and apple fruit russeting.

FEMS Yeast Res. 6(8) , 1149-56, (2006)

The effect of inoculations with yeasts occurring on apple surfaces and fungicide treatments on the russeting of Elstar apples was studied. Captan, dithianon and a water treatment were implemented to study the interaction between the fungicides, the inoculated...

Determination of residues of dithianon in apples by high-performance liquid chromatography.

Analyst 109(1) , 81-3, (1984)

Effect of 2,3-dinitrilo-1,4-dithia-9,10-antraquinone on Ehrlich ascites carcinoma and yeast cells.

Chem. Biol. Interact. 30(1) , 105-4, (1980)

The inhibition of glycolysis by 2,3-dinitrilo-1,4-dithia-9,10-antraquinone (DDA) in Ehrlich ascites carcinoma (EAC) cells as well as in the investigated respiratory and fermentative strains of yeasts was found to be the result of inactivation of thiol enzymes...