Bromo(trimethyl)silane
Bromo(trimethyl)silane structure
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Common Name | Bromo(trimethyl)silane | ||
|---|---|---|---|---|
| CAS Number | 2857-97-8 | Molecular Weight | 153.093 | |
| Density | 1.2±0.1 g/cm3 | Boiling Point | 79.0±0.0 °C at 760 mmHg | |
| Molecular Formula | C3H9BrSi | Melting Point | -43 °C | |
| MSDS | Chinese USA | Flash Point | -11.1±13.4 °C | |
| Symbol |
GHS02, GHS05 |
Signal Word | Danger | |
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EPR and NMR spectroscopies provide input on the coordination of Cu(I) and Ag(I) to a disordered methionine segment.
J. Biol. Inorg. Chem. 20 , 719-27, (2015) Methionine motifs are methionine-rich metal-binding segments found in many human, yeast, and bacterial proteins involved in the transportation of copper ion to other cellular pathways, and in protecting copper from oxidation. Methionine motifs are found to bi... |
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Position and length of fatty acids strongly affect receptor selectivity pattern of human pancreatic polypeptide analogues.
ChemMedChem 9(11) , 2463-74, (2014) Pancreatic polypeptide (PP) is a satiety-inducing gut hormone targeting predominantly the Y4 receptor within the neuropeptide Y multiligand/multireceptor family. Palmitoylated PP-based ligands have already been reported to exert prolonged satiety-inducing eff... |
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Reduced vascular endothelial growth factor and capillary density in the occipital cortex in dementia with Lewy bodies.
Brain Pathol. 24(4) , 334-43, (2014) In dementia with Lewy bodies (DLB), blood flow tends to be reduced in the occipital cortex. We previously showed elevated activity of the endothelin and angiotensin pathways in Alzheimer's disease (AD). We have measured endothelin-1 (ET-1) level and angiotens... |
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Two-step hard acid deprotection/cleavage procedure for solid phase peptide synthesis.
Int. J. Pept. Protein Res. 37(2) , 145-52, (1991) A new two-step deprotection/cleavage procedure for t-butoxycarbonyl (Boc) based solid phase peptide synthesis is reported. First the protective groups are removed from 4-(oxymethyl)-phenylacetamidomethyl (PAM) resin attached peptide with the weak hard acid, t... |
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The chemoselective and efficient deprotection of silyl ethers using trimethylsilyl bromide.
Org. Biomol. Chem. 6(12) , 2168-72, (2008) An efficient and chemoselective cleavage of silyl ethers (primary, secondary and aromatic) by using catalytic quantities of trimethylsilyl bromide (TMSBr) in methanol is reported. A wide range of alkyl silyl ethers such as TBS, TIPS, and TBDPS can be chemosel... |
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Capillary gas chromatography of hexadecylphosphocholine in Caco-2T cells and cell culture media.
Anal. Biochem. 227(1) , 246-50, (1995) The gas-chromatographic determination of hexadecylphosphocholine (HePC), an experimental antitumor agent of the alkyllysophospholipid group, in Caco-2T cell culture and cell culture media is described. The Caco-2T cells were treated with HePC at a concentrati... |
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Total synthesis of natural (+)-(2's,3'r)-zoapatanol.
Org. Lett. 6(13) , 2149-51, (2004) [reaction: see text] (+)-Zoapatanol was synthesized by using four key-steps: a Suzuki cross-coupling to prepare a (Z)-alpha,beta-unsaturated ester followed by an enantioselective dihydroxylation to control the C2' and C3' stereocenters, an intramolecular Horn... |
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Improvements to the TMSBr method of peptide resin deprotection and cleavage: application to large peptides.
Pept. Res. 9(5) , 218-22, (1996) The original trimethylsilyl bromide (TMSBr) method of peptide resin deprotection and cleavage has been modified for convenience and applicability to larger peptides. Equal amounts of a 66-residue test peptide resin were cleaved by the standard hydrogen fluori... |
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Cleavage and deprotection of peptide resins using chloro- and bromotrialkylsilanes.
Pept. Res. 8(5) , 298-300, (1995) The cleavage of a peptide resin attached to a phenylacetomidomethyl (PAM) resin was investigated using bromotrimethylsilane (TMSBr) with thioanisole in trifluoroacetic acid (TFA), and by chlorotrimethylsilane (TMSCl) in the same reagents with lithium bromide.... |
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[Development of new deprotecting methodologies for peptides and application to studies on signaling mechanism].
Yakugaku Zasshi 120(1) , 54-67, (2000) This review summarizes the development of deprotecting methodologies for peptides and their practical application to the synthesis of disulfide bond- or phosphoamino acid-containing peptides. Acidic deprotecting systems utilizing Brønsted acid (HF, trifluorom... |