9H-Purine,6-(ethylthio)-
9H-Purine,6-(ethylthio)- structure
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Common Name | 9H-Purine,6-(ethylthio)- | ||
|---|---|---|---|---|
| CAS Number | 5417-84-5 | Molecular Weight | 180.23000 | |
| Density | 1.39g/cm3 | Boiling Point | 460.2ºC at 760mmHg | |
| Molecular Formula | C7H8N4S | Melting Point | N/A | |
| MSDS | Chinese USA | Flash Point | 232.1ºC | |
| Symbol |
GHS08 |
Signal Word | Warning | |
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Induction of the c-ski proto-oncogene by phorbol ester correlates with induction of megakaryocyte differentiation.
Oncogene 9(5) , 1407-16, (1994) Overexpression of v-ski blocks the terminal differentiation of chicken erythroblasts, and in cooperation with v-sea causes transformation of these cells, indicating that c-ski may play a role in regulating either proliferation or differentiation in hematopoie... |
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6-ethylmercaptopurine-mediated growth inhibition of HL-60 cells in vitro irrespective of purine salvage.
Cancer Chemother. Pharmacol. 25(3) , 189-94, (1989) A variety of purine analogs inhibit the growth and induce the differentiation of human promyelocytic leukemia (HL-60) cells that lack the purine salvage enzyme hypoxanthine-guanine phosphoribosyltransferase (HGPRT). Mechanisms by which purine analogs induce d... |
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Differential effect of 6-ethylmercaptopurine on c-myc expression in wild-type and HGPRT-deficient HL-60 cells.
Cancer Chemother. Pharmacol. 27(3) , 171-7, (1990) A variety of compounds inhibit the growth and induce differentiation of human promyelocytic leukemia (HL-60) cells. HL-60 subclones that lack the purine salvage enzyme hypoxanthine-guanine phosphoribosyltransferase (HGPRT) can also be induced to differentiate... |