Ethoxyquin

Ethoxyquin Structure
Ethoxyquin structure
Common Name Ethoxyquin
CAS Number 91-53-2 Molecular Weight 217.307
Density 1.0±0.1 g/cm3 Boiling Point 333.1±42.0 °C at 760 mmHg
Molecular Formula C14H19NO Melting Point <0ºC
MSDS Chinese USA Flash Point 137.8±17.3 °C
Symbol GHS07
GHS07
Signal Word Warning

Modulation of ethoxyquin genotoxicity by free radical scavengers and DNA damage repair in human lymphocytes.

Toxicol. Lett. 193(2) , 194-9, (2010)

N-tert-butyl-alpha-phenylnitrone (PBN) and its new derivative N-(Pyridine-4-ylmethylidene)-2-carboxy-tert-butylamine N-oxide (PBNC) were synthesized and used to modulate ethoxyquin (1,2-dihydro-6-ethoxy-2,2,4-trimethylquinoline, EQ) genotoxicity. Ethoxyquin, ...

Effects of a dietary antioxidant blend and vitamin E on fatty acid profile, liver function, and inflammatory response in broiler chickens fed a diet high in oxidants.

Poult. Sci. 93(7) , 1658-66, (2014)

The aim of the current study was to determine the effects of a dietary antioxidant blend and vitamin E on fatty acid profile, inflammatory response, and liver function. Cobb 500 male broilers (n = 1,200, d 0) were randomly distributed into 6 treatments with 1...

Effects of a dietary antioxidant blend and vitamin E on growth performance, oxidative status, and meat quality in broiler chickens fed a diet high in oxidants.

Poult. Sci. 93(7) , 1649-57, (2014)

The aim of the study was to determine the effects of a dietary antioxidant blend (AB) and vitamin E on performance, oxidative status, and meat quality. Cobb 500 male broilers (n = 1,200, d 0) were randomly distributed into 6 treatments with 10 replicate pens....

Effect of antioxidant inclusion and oil quality on broiler performance, meat quality, and lipid oxidation.

Poult. Sci. 90(4) , 922-30, (2011)

The objective of the present study was to evaluate the effect of antioxidant inclusion and oil quality on broiler performance, meat quality, shelf life, and tissue oxidative status. Ross 308 male broilers were allotted to a randomized complete block design in...

Regulation of aldehyde reductase expression by STAF and CHOP.

Genomics 83(1) , 119-29, (2004)

Aldehyde reductase is involved in the reductive detoxification of reactive aldehydes that can modify cellular macromolecules. To analyze the mechanism of basal regulation of aldehyde reductase expression, we cloned the murine gene and adjacent regulatory regi...

Fate and effect of the antioxidant ethoxyquin on a mixed methanogenic culture.

Water Res. 39(17) , 4251-63, (2005)

The potential inhibitory effect of ethoxyquin, an antioxidant commonly used as a preservative in the food processing industry (e.g., for stabilizing dissolved air flotation residuals), was evaluated at concentrations up to 300 mg/L using a mixed, mesophilic (...

Investigations on the metabolism and potentially adverse effects of ethoxyquin dimer, a major metabolite of the synthetic antioxidant ethoxyquin in salmon muscle.

J. Food Prot. 74(9) , 1574-80, (2011)

The feed additive ethoxyquin (EQ) is a commonly used synthetic antioxidant preservative in animal feeds. In farmed Atlantic salmon fillets, EQ residues are present, both as the parent compound and as EQ derivatives. One of the main EQ derivates in fish muscle...

Induced expression of drug metabolizing enzymes by preventive agents: role of the antioxidant response element.

Chem. Biol. Interact. 182(1) , 22-8, (2009)

Identifying agents that block tumor initiation is a goal of cancer prevention. The ability of a chemically varied group of agents to induce various drug metabolizing genes in livers of rats was examined. Sprague-Dawley rats were treated for 7 days with variou...

Simultaneous quantitative determination of the synthetic antioxidant ethoxyquin and its major metabolite in Atlantic salmon (Salmo salar, L), ethoxyquin dimer, by reversed-phase high-performance liquid chromatography with fluorescence detection.

J. AOAC Int. 90(2) , 587-97, (2007)

A method for simultaneous quantitative determination of ethoxyquin (EQ) and its major metabolite in Atlantic salmon tissues, ethoxyquin dimer (EQ dimer), has been developed. The separation was achieved on tandem coupled phenyl-hexyl and C18 columns by 2-phase...

Genotoxic and antioxidant activities of ethoxyquin salts evaluated by the comet assay.

Chem. Biol. Interact. 162(3) , 268-73, (2006)

Four newly synthesized salts of ethoxyquin (EQ: 1,2-dihydro-6-ethoxy-2,2,4-trimethylquinoline), an antioxidant used in animal feeds, were evaluated with the use of the comet assay performed on human lymphocytes: ethoxyquin ascorbate, ethoxyquin hexanoate, eth...