pyranocoumarin
pyranocoumarin structure
|
Common Name | pyranocoumarin | ||
|---|---|---|---|---|
| CAS Number | 518-20-7 | Molecular Weight | 322.35500 | |
| Density | 1.27g/cm3 | Boiling Point | 488.6ºC at 760 mmHg | |
| Molecular Formula | C20H18O4 | Melting Point | 166° | |
| MSDS | Chinese USA | Flash Point | 216.2ºC | |
| Symbol |
GHS06 |
Signal Word | Danger | |
|
The preferred solution conformation of warfarin at the active site of cytochrome P-450 based on the CD spectra in octanol/water model system.
J. Med. Chem. 27(8) , 1092-5, (1984) An octanol/water model system and circular dichroism (CD) spectroscopy have been used to study the solution conformation of warfarin in aqueous and lipid environments. Upon partitioning of (S)-warfarin from buffer pH 7.4 into octanol, the position of the abso... |
|
|
Structural forms of phenprocoumon and warfarin that are metabolized at the active site of CYP2C9.
Arch. Biochem. Biophys. 372(1) , 16-28, (1999) Possible reasons for the observed differences in metabolic behavior and drug interaction liability between the structurally similar oral anticoagulants warfarin and phenprocoumon were explored. Incubating (S)-phenprocoumon with human liver microsomes and cDNA... |
|
|
Inhibitory effect of coumarins on HIV-1 replication and cell-mediated or cell-free viral transmission.
Acta Virol. 37(4) , 241-50, (1993) A single dose of coumarin derivatives, warfarin, 4-hydroxycoumarin and umbelliferone, added at the time of inoculation either by free virus or by contact with U1 monocytes exhibited a dose-dependent inhibitory effect on viral replication in target MOLT-4 lymp... |