Shikimic acid
Shikimic acid structure
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Common Name | Shikimic acid | ||
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| CAS Number | 138-59-0 | Molecular Weight | 174.151 | |
| Density | 1.7±0.1 g/cm3 | Boiling Point | 400.5±45.0 °C at 760 mmHg | |
| Molecular Formula | C7H10O5 | Melting Point | 185-187 °C(lit.) | |
| MSDS | Chinese USA | Flash Point | 210.1±25.2 °C | |
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Binding and Anticancer Properties of Plumbagin with Human Serum Albumin.
Chem. Biol. Drug Des. 86 , 362-9, (2015) Plumbagin has received extensive attention as a promising anticancer drug. Therefore, we investigated the binding and anticancer properties of plumbagin with human serum albumin. Fluorescence results demonstrated that plumbagin interacts with human serum albu... |
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Metabolomic profiles delineate potential role for sarcosine in prostate cancer progression.
Nature 457(7231) , 910-4, (2009) Multiple, complex molecular events characterize cancer development and progression. Deciphering the molecular networks that distinguish organ-confined disease from metastatic disease may lead to the identification of critical biomarkers for cancer invasion an... |
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A metabolite profiling approach to identify biomarkers of flavonoid intake in humans.
J. Nucl. Med. 139 , 2309-14, (2009) Flavonoids are phytochemicals that are widespread in the human diet. Despite limitations in their bioavailability, experimental and epidemiological data suggest health benefits of flavonoid consumption. Valid biomarkers of flavonoid intake may be useful for e... |
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A national reconnaissance for selected organic micropollutants in sediments on French territory.
Environ. Sci. Pollut. Res. Int. 21(19) , 11370-9, (2014) To collect a large data set regarding the occurrence of organic substances in sediment, this study presents the examination of 20 micropollutants, as a national survey. The list of target compounds contains two alkylphenols, three polycyclic aromatic hydrocar... |
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Shikimic acid ozonolysis kinetics of the transition from liquid aqueous solution to highly viscous glass.
Phys. Chem. Chem. Phys. 17 , 31101-9, (2015) Ageing of particulate organic matter affects the composition and properties of atmospheric aerosol particles. Driven by temperature and humidity, the organic fraction can vary its physical state between liquid and amorphous solid, or rarely even crystalline. ... |
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Study of the retention behavior of small polar molecules on different types of stationary phases used in hydrophilic interaction liquid chromatography.
J. Sep. Sci. 37(11) , 1297-307, (2014) The retention behavior of a large group of analytes (35) with varied properties (pKa and logP) was studied on eight hydrophilic interaction LC columns with different surfaces, stationary phase chemistries, and types of particles. The acetonitrile content (5-9... |
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UHPLC-PDA-ESI-TOF/MS metabolic profiling of Arctostaphylos pungens and Arctostaphylos uva-ursi. A comparative study of phenolic compounds from leaf methanolic extracts.
Phytochemistry 115 , 79-88, (2015) The aim of this study was to get a rapid metabolic fingerprinting and to gain insight into the metabolic profiling of Arctostaphylos pungens H. B. K., a plant morphologically similar to Arctostaphylos uva-ursi (L.) Spreng. (bearberry) but with a lower arbutin... |
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Rational design of novel, potent small molecule pan-selectin antagonists.
J. Med. Chem. 50 , 1101-1115, (2007) This report describes the first results of a rational hit-finding strategy to design novel small molecule antiinflammatory drugs targeting selectins, a family of three cellular adhesion molecules. Based on recent progress in understanding of molecular interac... |
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In Vitro Neuroprotective Effect of Shikimic Acid Against Hydrogen Peroxide-Induced Oxidative Stress.
J. Mol. Neurosci. 56 , 956-65, (2015) Shikimic acid (SA), originally extracted from Illicium verum Hook. fil., is an indispensable starting material for the synthesis of the antiviral drug Oseltamivir (Tamiflu(®)) with very limited number of studies regarding its biological effects in vitro. Ther... |
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Enzyme-substrate complexes of the quinate/shikimate dehydrogenase from Corynebacterium glutamicum enable new insights in substrate and cofactor binding, specificity, and discrimination.
Biol. Chem. 394(11) , 1505-16, (2013) Quinate dehydrogenase (QDH) catalyzes the reversible oxidation of quinate to 3-dehydroquinate by nicotineamide adenine dinucleotide (NADH) and is involved in the catabolic quinate metabolism required for the degradation of lignin. The enzyme is a member of th... |