Agomelatine
Agomelatine structure
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Common Name | Agomelatine | ||
|---|---|---|---|---|
| CAS Number | 138112-76-2 | Molecular Weight | 243.301 | |
| Density | 1.1±0.1 g/cm3 | Boiling Point | 478.8±28.0 °C at 760 mmHg | |
| Molecular Formula | C15H17NO2 | Melting Point | 107-109ºC | |
| MSDS | Chinese USA | Flash Point | 243.4±24.0 °C | |
| Symbol |
GHS09 |
Signal Word | Warning | |
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[The activity of glutathione antioxidant system at melaksen and valdoxan action under experimental hyperthyroidism in rats].
Biomed. Khim. 59(5) , 541-9, (2013) Investigation of glutathione antioxidant system activity and diene conjugates content in rats liver and blood serum at the influence of melaksen and valdoxan under experimental hyperthyroidism (EG) has been revealed. It has been established that the activitie... |
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[Tachycardia and precordial pain with agomelatine: a case report].
Therapie. 68(5) , 324-5, (2013)
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Agomelatine, melatonin and depressive disorder.
Expert Opin. Investig. Drugs 22(4) , 407-10, (2013) Alteration of nocturnal melatonin production, along with circadian rhythm disturbance, has been demonstrated in several psychiatric disorders. It has been postulated that such disturbances might be causal reflecting a more fundamental abnormality of the funct... |
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Agomelatine may improve REM sleep behavior disorder symptoms.
J. Clin. Psychopharmacol. 32(5) , 732-4, (2012)
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A naturalistic evaluation and audit database of agomelatine: clinical outcome at 12 weeks.
Acta Psychiatr. Scand. 128(3) , 203-11, (2013) To determine the effectiveness of agomelatine in routine clinical practice and explore factors associated with response and continuation.Consecutive patients prescribed agomelatine in participating psychiatric services were included. Patient demographic and o... |
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Melatonin analogue agomelatine reduces rabbit's intraocular pressure in normotensive and hypertensive conditions.
Eur. J. Pharmacol. 701(1-3) , 213-7, (2013) In the search for new compounds to reduce intraocular pressure (IOP), with fewer side effects, we have found that agomelatine, a melatonin analogue, can reduce IOP being, therefore, interesting for the treatment of ocular hypertension and glaucoma. In normote... |
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Treatment of severe sleep disorder related to alcohol-dependence with high-dose agomelatine - a case report.
Psychiatr. Danub. 25(4) , 416-8, (2013)
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Agomelatine versus other antidepressive agents for major depression.
Cochrane Database Syst. Rev. 12 , CD008851, (2013) Major depressive disorder (MDD), or depression, is a syndrome characterised by a number of behavioural, cognitive and emotional features. It is most commonly associated with a sad or depressed mood, a reduced capacity to feel pleasure, feelings of hopelessnes... |
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Economic evaluation of agomelatine relative to other antidepressants for treatment of major depressive disorders in Greece.
BMC Health Serv. Res. 13 , 173, (2013) Major depressive disorder (MDD) constitutes an important public health problem, as it is highly prevalent in the industrialized world and it is associated with substantial economic consequences for patients, health care providers, insurance and social securit... |
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Two cases of delirium with agomelatine therapy.
Ann. Clin. Psychiatry 25(1) , 67-8, (2013)
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