2(3H)-Furanone,3-aminodihydro-, hydrobromide (1:1)
2(3H)-Furanone,3-aminodihydro-, hydrobromide (1:1) structure
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Common Name | 2(3H)-Furanone,3-aminodihydro-, hydrobromide (1:1) | ||
|---|---|---|---|---|
| CAS Number | 6305-38-0 | Molecular Weight | 182.01600 | |
| Density | N/A | Boiling Point | 257.1ºC at 760 mmHg | |
| Molecular Formula | C4H8BrNO2 | Melting Point | 220-225 °C(lit.) | |
| MSDS | Chinese USA | Flash Point | 120.1ºC | |
| Symbol |
GHS07 |
Signal Word | Warning | |
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Catalytic asymmetric construction of spiro(γ-butyrolactam-γ-butyrolactone) moieties through sequential reactions of cyclic imino esters with Morita-Baylis-Hillman bromides.
Chemistry 18(40) , 12614-8, (2012) Spiro(γ-butyrolactam-γ-butyrolactone): a route to enantioenriched spiro(γ-butyrolactam-γ-butyrolactone) compounds, a valuable motif for drug discovery, was developed by use of a highly efficient copper(I)/TF-BiphamPhos-catalyzed tandem Michael addition-elimin... |
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[The influence of bacterial autoregulation molecules (homoserine lactones and alkyloxybenzoles) on oxidative metabolism of the natural immunity cellular effectors].
Mikrobiologiia 82(2) , 147-56, (2013)
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Thapsigargin blocks Pseudomonas aeruginosa homoserine lactone-induced apoptosis in airway epithelia.
Am. J. Physiol. Cell Physiol. 306(9) , C844-55, (2014) Pseudomonas aeruginosa secretes N-(3-oxododecanoyl)-homoserine lactone (C12) as a quorum-sensing molecule to regulate gene expression. Micromolar concentrations are found in the airway surface liquid of infected lungs. Exposure of the airway surface to C12 ca... |
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Identification and characterization of a second quorum-sensing system in Agrobacterium tumefaciens A6.
J. Bacteriol. 196(7) , 1403-11, (2014) Quorum sensing (QS) is a widespread mechanism of bacterial communication in which individual cells produce and respond to small chemical signals. In Agrobacterium tumefaciens, an acylhomoserine lactone-dependent QS mechanism is known to regulate the replicati... |
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The bacterial quorum-sensing signal molecule N-3-oxo-dodecanoyl-L-homoserine lactone reciprocally modulates pro- and anti-inflammatory cytokines in activated macrophages.
J. Immunol. 191(1) , 337-44, (2013) The bacterial molecule N-3-oxo-dodecanoyl-l-homoserine lactone (C12) has critical roles in both interbacterial communication and interkingdom signaling. The ability of C12 to downregulate production of the key proinflammatory cytokine TNF-α in stimulated macr... |
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Effect of N-acy-l-homoserine lactones-like molecules from aerobic granules on biofilm formation by Escherichia coli K12.
Bioresour. Technol. 129 , 655-8, (2013) A laboratory study was conducted to investigate the production of quorum sensing (QS) molecules by aerobic granules in membrane-partitioned bioreactor. Flow-chamber (FC) tests with Escherichia coli K12 demonstrated that granules induced more attached growth o... |
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O-Succinyl-L-homoserine-based C4-chemical production: succinic acid, homoserine lactone, γ-butyrolactone, γ-butyrolactone derivatives, and 1,4-butanediol.
J. Ind. Microbiol. Biotechnol. 41(10) , 1517-24, (2014) There has been a significant global interest to produce bulk chemicals from renewable resources using engineered microorganisms. Large research programs have been launched by academia and industry towards this goal. Particularly, C4 chemicals such as succinic... |
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Design, synthesis and biological evaluation of N-sulfonyl homoserine lactone derivatives as inhibitors of quorum sensing in Chromobacterium violaceum.
Molecules 18(3) , 3266-78, (2013) A novel series of N-sulfonyl homoserine lactone derivatives 5a-l has been designed, synthesized and evaluated for quorum sensing inhibitory activities towards violacein production. Of the compounds synthesized, compound 5h was found to possess an excellent le... |
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Kinetic modeling of the time course of N-butyryl-homoserine lactone concentration during batch cultivations of Pseudomonas aeruginosa PAO1.
Appl. Microbiol. Biotechnol. 97(17) , 7607-16, (2013) Quorum sensing affects the regulation of more than 300 genes in Pseudomonas aeruginosa, influencing growth, biofilm formation, and the biosynthesis of several products. The quorum sensing regulation mechanisms are mostly described in a qualitative character. ... |
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Immunomodulation and the quorum sensing molecule 3-oxo-C12-homoserine lactone: the importance of chemical scaffolding for probe development.
Chem. Commun. (Camb.) 49(15) , 1515-7, (2013) As a guide for chemical probe design, focused analogue synthetic studies were undertaken upon the lactone ring of 3-oxo-C(12)-homoserine lactone. We have concluded that hydrolytic instability of the heterocyclic ring is pivotal for its ability to modulate imm... |