Pyridin-3-ol
Pyridin-3-ol structure
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Common Name | Pyridin-3-ol | ||
|---|---|---|---|---|
| CAS Number | 109-00-2 | Molecular Weight | 95.099 | |
| Density | 1.2±0.1 g/cm3 | Boiling Point | 318.9±0.0 °C at 760 mmHg | |
| Molecular Formula | C5H5NO | Melting Point | 125-128 °C(lit.) | |
| MSDS | Chinese USA | Flash Point | 146.6±20.4 °C | |
| Symbol |
GHS07 |
Signal Word | Warning | |
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Combination of Genistein and Cisplatin with Two Designed Monofunctional Platinum Agents in Human Ovarian Tumour Models.
Anticancer Res. 35 , 6027-39, (2015) A great amount of research effort has been directed at platinum compounds that bind with DNA differently from cisplatin with the idea that the difference may translate into an altered spectrum of activity. Recently research has also been directed at applying ... |
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Preparative-scale isoelectric trapping by recursive electrophoresis in a compartmentalized system having orthogonal primary and secondary pH gradients. Part 2--operation in cascade mode.
Electrophoresis 32(20) , 2805-8, (2011) A parallel multicompartmental electrolyzer recently developed for preparative-scale isoelectric trapping separations, trapping by recursive electrophoresis in a compartmentalized system, was set up to operate as a cascade of binary separations to produce at l... |
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Preparative-scale isoelectric trapping by recursive electrophoresis in a compartmentalized system having orthogonal primary and secondary pH gradients. Part 1--construction and standard operation.
Electrophoresis 32(20) , 2797-804, (2011) The performance of the current preparative-scale isoelectric trapping systems is limited by the serial arrangement of the separation compartments. A new system has been developed that achieves trapping by recursive electrophoresis in a compartmentalized syste... |
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Characterization of subdomain IIA binding site of human serum albumin in its native, unfolded, and refolded states using small molecular probes.
J. Am. Chem. Soc. 130(32) , 10793-801, (2008) Subdomain IIA binding site of human serum albumin (HSA) was characterized by examining the change in HSA fluorescence in the native, unfolded, and refolded states. The study was carried out in the absence and presence of small molecular probes using steady-st... |
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Lipid-soluble 3-pyridinol antioxidants spare alpha-tocopherol and do not efficiently mediate peroxidation of cholesterol esters in human low-density lipoprotein.
J. Med. Chem. 48(22) , 6787-9, (2005) Because alpha-tocopherol (alpha-TOH) mediates the peroxidation of cholesterol-esterified lipids in human low-density lipoprotein (LDL) in vitro and has displayed disappointing results against the onset and development of atherosclerosis, it may not be appropr... |
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Tautomerism and possible polymorphism in solid hydroxypyridines and pyridones studied by 14N NQR.
J. Phys. Chem. A 117(7) , 1651-8, (2013) (14)N nuclear quadrupole resonance frequencies have been measured in solid 2-pyridone, 3-hydroxypyridine, and 4-pyridone by (1)H-(14)N nuclear quadrupole double resonance. Two slightly nonequivalent nitrogen positions are observed in solid 3-hydroxypyridine, ... |
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The synthesis and preclinical evaluation in rhesus monkey of [¹⁸F]MK-6577 and [¹¹C]CMPyPB glycine transporter 1 positron emission tomography radiotracers.
Synapse 65(4) , 261-70, (2011) Two positron emission tomography radiotracers for the glycine transporter 1 (GlyT1) are reported here. Each radiotracer is a propylsulfonamide-containing benzamide and was labeled with either carbon-11 or fluorine-18. [¹¹C]CMPyPB was synthesized by the alkyla... |
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CYP1A1 induction by pyridine and its metabolites in HepG2 cells.
Arch. Biochem. Biophys. 404(2) , 326-34, (2002) Pyridine and its metabolites have been shown in previous studies to induce cytochrome P4501A1 (CYP1A1) expression in vivo in the rat and in vitro in cultured human lung explants. In this study, we assessed the role of the metabolites in CYP1A1 induction by th... |
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Quantitative method for biomarkers of collagen degradation using liquid chromatography tandem mass spectrometry.
Anal. Biochem. 283(1) , 71-6, (2000) Preclinical efficacy testing commonly involves studies that require considerable resources and time. One valuable tool in this endeavor is the characterization of relevant biomarkers. A method has been developed for the simultaneous determination of collagen ... |
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Enzymatic synthesis of aza-l-tyrosines.
Bioorg. Med. Chem. Lett. 11(16) , 2099-100, (2001) Tyrosine phenol-lyase from Citrobacter freundii synthesizes 2-aza-L-tyrosine and 3-aza-L-tyrosine from 3-hydroxypyridine and 2-hydroxypyridine, respectively, and ammonium pyruvate. |