Bioorganic & Medicinal Chemistry Letters 2001-08-20

Enzymatic synthesis of aza-l-tyrosines.

E B Watkins, R S Phillips

Index: Bioorg. Med. Chem. Lett. 11(16) , 2099-100, (2001)

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Abstract

Tyrosine phenol-lyase from Citrobacter freundii synthesizes 2-aza-L-tyrosine and 3-aza-L-tyrosine from 3-hydroxypyridine and 2-hydroxypyridine, respectively, and ammonium pyruvate.