D-MYO-INOSITOL 4,5-BIS-PHOSPHATE AMMONIUM SALT
D-MYO-INOSITOL 4,5-BIS-PHOSPHATE AMMONIUM SALT structure
|
Common Name | D-MYO-INOSITOL 4,5-BIS-PHOSPHATE AMMONIUM SALT | ||
|---|---|---|---|---|
| CAS Number | 69256-54-8 | Molecular Weight | 357.14600 | |
| Density | N/A | Boiling Point | N/A | |
| Molecular Formula | C6H17NO12P2 | Melting Point | N/A | |
| MSDS | Chinese USA | Flash Point | N/A | |
|
Antigen-induced Ca2+ mobilization in RBL-2H3 cells: role of I(1,4,5)P3 and S1P and necessity of I(1,4,5)P3 production.
Cell Calcium 38(6) , 581-92, (2005) Inositol 1,4,5-trisphosphate (IP3) has long been recognized as a second messenger for intracellular Ca2+ mobilization. Recently, sphingosine 1-phosphate (S1P) has been shown to be involved in Ca2+ release from the endoplasmic reticulum (ER). Here, we investig... |
|
|
Evidence for lithium-sensitive inositol 4,5-bisphosphate accumulation in muscarinic cholinoceptor-stimulated cerebral-cortex slices.
Biochem. J. 287 ( Pt 2) , 437-42, (1992) Stimulation of [3H]inositol-prelabelled rat cerebral-cortex slices with carbachol results in the accumulation of four [3H]inositol bisphosphate isomeric species, Ins(1,3)P2, Ins(1,4)P2, Ins(3,4)P2 and Ins(4,5)P2. Although the last isomer ran as a minor peak o... |
|
|
Action and formation of inositol bisphosphate and inositol trisphosphate in rat anterior pituitary cells.
Acta Endocrinol. 123(4) , 459-63, (1990) Inositol 4,5-bisphosphate and inositol 1,4,5-trisphosphate, administered exogenously at a concentration of 3 x 10(-5) mol/l increased LH release in superfused rat pituitary cells by 950 +/- 267% and 281 +/- 83%, respectively. This stimulatory effect was rever... |
|
|
Pathways of dephosphorylation of 1-D-myo-inositol 1,4,5-trisphosphate in GH3 pituitary tumor cells.
Biochim. Biophys. Acta 1178(1) , 63-72, (1993) Previous work in [3H]inositol-labelled GH3 pituitary tumor cells stimulated with thyrotropin-releasing hormone (TRH) reported the existence of at least ten distinct [3H]inositol-containing substances which were identified as different inositol mono-, bis- and... |
|
|
P2Y(2) receptor-stimulated phosphoinositide hydrolysis and Ca(2+) mobilization in tracheal epithelial cells.
Am. J. Physiol. Lung Cell. Mol. Physiol. 279(2) , L235-41, (2000) Extracellular nucleotides have been implicated in the regulation of secretory function through the activation of P2 receptors in the epithelial tissues, including tracheal epithelial cells (TECs). In this study, experiments were conducted to characterize the ... |
|
|
Somatostatin inhibition of phosphoinositides turnover in isolated rat acinar pancreatic cells: interaction with bombesin.
Regul. Pept. 41(3) , 219-26, (1992) The effects of somatostatin-14 and bombesin on [3H]inositol phosphate accumulation were studied in 24 h myo-[3H]inositol-prelabeled cultured rat acinar cells. Bombesin, 10 nM, stimulated basal formation of phosphatidyl monophosphate (InsP1), phosphatidyl 4,5-... |
|
|
The pleckstrin homology domain of Gab-2 is required for optimal interleukin-3 signalsome-mediated responses.
Cell. Signal. 18(8) , 1147-55, (2006) The adaptor protein Gab-2 coordinates the assembly of the IL-3 signalsome comprising Gab-2, Grb2, Shc, SHP-2 and PI3K. To investigate the role of the pleckstrin homology domain of Gab-2 in this process, epitope-tagged wild type Gab-2 (WTGab-2), Gab-2 lacking ... |
|
|
Dieldrin modifies the hydrolysis of PIP2 and decreases the fertilization rate in Bufo arenarum oocytes.
Comp. Biochem. Physiol. C, Pharmacol. Toxicol. Endocrinol. 112(1) , 61-7, (1995) Carbachol treatment in Bufo arenarum oocytes decreases the radioactivity in [32P]PIP2 in the following 20 min after stimulation and increases the [3H]glycerol labeling of 1,2-DAG at 1 min of stimulation. On the contrary, in Dieldrin treated oocytes carbachol ... |
|
|
A novel phospholipase C delta4 (PLCdelta4) splice variant as a negative regulator of PLC.
J. Biol. Chem. 274(5) , 2872-9, (1999) It has been reported that there are two alternatively spliced variants of phospholipase C-delta4 (PLCdelta4), termed ALT I and II, that contain an additional 32 and 14 amino acids in their respective sequences in the linker region between the catalytic X and ... |
|
|
[Cellular mechanisms of calcium regulation of cardiac rhythm in children with ectopic arrhythmias].
Vopr. Med. Khim. 40(4) , 50-3, (1994) Regulation of intracellular calcium homeostasis by means of secondary mediators calmodulin and 4,5-inositol phosphates (products of phosphatidyl inositol hydrolysis) was studied in children with ectopic forms of arrhythmias. Alterations in the system calmodul... |