ALPHA-METHYLPHENYLACETONITRILE

ALPHA-METHYLPHENYLACETONITRILE Structure
ALPHA-METHYLPHENYLACETONITRILE structure
Common Name ALPHA-METHYLPHENYLACETONITRILE
CAS Number 1823-91-2 Molecular Weight 131.17400
Density 0.985 g/mL at 25 °C(lit.) Boiling Point 231 °C
Molecular Formula C9H9N Melting Point N/A
MSDS Chinese USA Flash Point 201 °F
Symbol GHS07
GHS07
Signal Word Warning

Conversion of sterically demanding α,α-disubstituted phenylacetonitriles by the arylacetonitrilase from Pseudomonas fluorescens EBC191.

Appl. Environ. Microbiol. 78 , 48 - 57, (2012)

The nitrilase from Pseudomonas fluorescens EBC191 converted 2-methyl-2-phenylpropionitrile, which contains a quaternary carbon atom in the α-position toward the nitrile group, and also similar sterically demanding substrates, such as 2-hydroxy-2-phenylpropion...

Heterologous expression, purification and characterization of nitrilase from Aspergillus niger K10.

BMC Biotechnol. 11 , 2, (2011)

Nitrilases attract increasing attention due to their utility in the mild hydrolysis of nitriles. According to activity and gene screening, filamentous fungi are a rich source of nitrilases distinct in evolution from their widely examined bacterial counterpart...

Production of S-(+)-2-phenylpropionic acid from (R,S)-2-phenylpropionitrile by the combination of nitrile hydratase and stereoselective amidase in Rhodococcus equi TG328.

Appl. Microbiol. Biotechnol. 39(6) , 720-5, (1993)

A new soil isolate, tentatively identified as Rhodococcus equi TG328, was found to be effective in the production of S-(+)-2-phenylpropionic acid from (R,S)-2-phenylpropionitrile. The conversion is catalysed by two enzymes. First, a nitrile hydratase converts...

Utilization of arylaliphatic nitriles by haloalkaliphilic Halomonas nitrilicus sp. nov. isolated from soda soils.

Appl. Microbiol. Biotechnol. 81(2) , 371-8, (2008)

An enrichment culture from saline soda soils, using acetate as carbon and energy source and 2-phenylpropionitrile as nitrogen source (PPN) at pH 10, resulted in the isolation of strain ANL-alpha CH3. The strain was identified as a representative of the genus ...

Enhancement of enzyme activity and enantioselectivity via cultivation in nitrile metabolism by Rhodococcus sp. CGMCC 0497.

Biotechnol. Appl. Biochem. 35(Pt 1) , 61-7, (2002)

Racemic 2-phenylpropionitrile was resolved enantioselectively by nitrile-converting enzymes in cells of Rhodococcus sp. CGMCC 0497 to S-(+)-2-phenylpropionic acid and R-(-)-2-phenylpropionamide. By optimization of the culture conditions, great enhancement of ...