D-4-Chlorophenylalanine
D-4-Chlorophenylalanine structure
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Common Name | D-4-Chlorophenylalanine | ||
|---|---|---|---|---|
| CAS Number | 14091-08-8 | Molecular Weight | 199.634 | |
| Density | 1.3±0.1 g/cm3 | Boiling Point | 339.5±32.0 °C at 760 mmHg | |
| Molecular Formula | C9H10ClNO2 | Melting Point | N/A | |
| MSDS | Chinese USA | Flash Point | 159.1±25.1 °C | |
| Symbol |
GHS06 |
Signal Word | Danger | |
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Antidepressant-like activity of ellagic acid in unstressed and acute immobilization-induced stressed mice.
Pharmacol. Rep. 64(4) , 796-807, (2012) The aim of present study was to evaluate antidepressant-like activity of ellagic acid in Swiss young male albino mice; and to explore the possible underlying mechanisms for this activity.Mice were immobilized for 150 min once only for induction of stress. Ell... |
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Dual role of serotonin in the pathogenesis of indomethacin-induced small intestinal ulceration: pro-ulcerogenic action via 5-HT3 receptors and anti-ulcerogenic action via 5-HT4 receptors.
Pharmacol. Res. 66(3) , 226-34, (2012) Serotonin (5-HT) exerts multiple physiological functions not only in the central and peripheral nervous systems but also in the gastrointestinal tract, and these multiple functions are accounted for by a variety of 5-HT receptor subtypes. We investigated the ... |
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A possible participation of transient receptor potential vanilloid type 1 channels in the antidepressant effect of fluoxetine
Eur. J. Pharmacol. 685(1-3) , 81-90, (2012) The present study investigated the influence of transient receptor vanilloid type 1 (TRPV1) channel agonist (capsaicin) and antagonist (capsazepine) either alone or in combination with traditional antidepressant drug, fluoxetine; or a serotonin hydroxylase in... |
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Pharmacological mechanisms of antidepressant-like effect of tipepidine in the forced swimming test
Behav. Brain Res. 226(2) , 381-5, (2012) Highlights ► Tipepidine produces an antidepressant like effect in the forced swimming test. ► The effect of tipepidine may be produced via dopamine D 1 and alpha2 adrenoceptor. ► The properties of the effect may be different from those of known antidepressant... |
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A pharmacological evidence of positive association between mouse intermale aggression and brain serotonin metabolism.
Behav. Brain Res. 233(1) , 113-9, (2012) The neurotransmitter serotonin (5-HT) is involved in the regulation of mouse intermale aggression. Previously, it was shown that intensity of mouse intermale aggression was positively associated with activity of the key enzyme of 5-HT synthesis - tryptophan h... |
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A test to determine the nature and presence of the memory effect columns packed with the amylose tris(3,5-dimethylphenylcarbamate) stationary phase.
J. Chromatogr. A. 1218(37) , 6302-7, (2011) Acid/base mobile phase modifiers affect enantioseparations in ways that are not fully understood yet, for the lack of systematic studies. This makes chiral analysis of some pharmaceuticals difficult to reproduce. Once a column has been exposed to a modifier, ... |
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Induction of glucose intolerance by acute administration of rimonabant.
Pharmacology 89(5-6) , 339-47, (2012) Rimonabant is a cannabinoid CB1 receptor antagonist. Other CB1 antagonists have biphasic effects on blood glucose levels following acute administration. We therefore tested the effects of rimonabant on glucose tolerance following acute administration.We teste... |
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AMPA glutamate receptors mediate the antidepressant-like effects of N-acetylcysteine in the mouse tail suspension test.
Behav. Pharmacol. 23(2) , 171-7, (2012) The aim of this study was to investigate the involvement of noradrenaline, serotonin, and subtypes of glutamate receptors in the antidepressant-like effects of N-acetylcysteine (NAC). The tail suspension test was used with male CF1 albino mice. D,L-α-methyl-ρ... |
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c-Fos activity mapping reveals differential effects of noradrenaline and serotonin depletion on the regulation of ocular dominance plasticity in rats.
Neuroscience 235 , 1-9, (2013) The roles of the central noradrenergic and serotonergic system in the activity-dependent regulation of ocular dominance plasticity have been a contentious issue. Using c-Fos activity mapping, we have developed a new, straightforward method to measure the stre... |
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On the presence of serotonin in mammalian cardiomyocytes.
Mol. Cell Biochem. 365(1-2) , 301-12, (2012) Pleiotropic effects of serotonin (5-HT) in the cardiovascular system are well documented. However, it remains to be elucidated, whether 5-HT is present in adult mammalian cardiomyocytes. To address this issue, we investigated the levels of 5-HT in blood, plas... |