Behavioural Brain Research 2012-01-01

Pharmacological mechanisms of antidepressant-like effect of tipepidine in the forced swimming test

Kazuaki Kawaura, Risa Miki, Yuri Urashima, Ryo Kawahara, Fumio Soeda, Tetsuya Shirasaki, Kazuo Takahama, Kazuaki Kawaura, Risa Miki, Yuri Urashima, Ryo Kawahara, Fumio Soeda, Tetsuya Shirasaki, Kazuo Takahama, Kazuaki Kawaura, Risa Miki, Yuri Urashima, Ryo Kawahara, Fumio Soeda, Tetsuya Shirasaki, Kazuo Takahama

Index: Behav. Brain Res. 226(2) , 381-5, (2012)

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Abstract

Highlights ► Tipepidine produces an antidepressant like effect in the forced swimming test. ► The effect of tipepidine may be produced via dopamine D 1 and alpha2 adrenoceptor. ► The properties of the effect may be different from those of known antidepressants.