DL-4-Chlorophenylalanine
DL-4-Chlorophenylalanine structure
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Common Name | DL-4-Chlorophenylalanine | ||
|---|---|---|---|---|
| CAS Number | 7424-00-2 | Molecular Weight | 199.634 | |
| Density | 1.3±0.1 g/cm3 | Boiling Point | 339.5±32.0 °C at 760 mmHg | |
| Molecular Formula | C9H10ClNO2 | Melting Point | >240 °C (dec.)(lit.) | |
| MSDS | Chinese USA | Flash Point | 159.1±25.1 °C | |
| Symbol |
GHS06 |
Signal Word | Danger | |
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Inhibitory Effect of Dried Pomegranate Concentration Powder on Melanogenesis in B16F10 Melanoma Cells; Involvement of p38 and PKA Signaling Pathways.
Int. J. Mol. Sci. 16 , 24219-42, (2015) Plants rich in antioxidant substances may be useful for preventing skin aging. Pomegranates, containing flavonoids and other polyphenolic compounds, are widely consumed due to their beneficial properties. We examined the underlying mechanisms of dried pomegra... |
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Chemical genetics reveals a complex functional ground state of neural stem cells.
Nat. Chem. Biol. 3(5) , 268-273, (2007) The identification of self-renewing and multipotent neural stem cells (NSCs) in the mammalian brain holds promise for the treatment of neurological diseases and has yielded new insight into brain cancer. However, the complete repertoire of signaling pathways ... |
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The natural basil flavonoid nevadensin protects against a methyleugenol-induced marker of hepatocarcinogenicity in male F344 rat.
Food Chem. Toxicol. 74 , 28-34, (2014) The alkenylbenzene methyleugenol occurs naturally in a variety of spices and herbs, including basil, and their essential oils. At high dose levels methyleugenol induces hepatocarcinogenicity in rodents following bioactivation to 1'-sulfooxymethyleugenol which... |
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Two-dimensional LC-MS/MS to enhance ceramide and phosphatidylcholine species profiling in mouse liver.
Biomed. Chromatogr. 28(9) , 1284-93, (2014) A two-dimensional (2D) hydrophilic interaction liquid chromatography (HILIC) and reverse-phase (RP) liquid chromatography (LC) system coupled with triple-quadrupole mass spectrometry (MS) was developed to comprehensively profile ceramides and phosphatidylchol... |
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Cytochrome P450 OxyBtei catalyzes the first phenolic coupling step in teicoplanin biosynthesis.
ChemBioChem. 15(18) , 2719-28, (2014) Bacterial cytochrome P450s form a remarkable clade of the P450 superfamily of oxidative hemoproteins, and are often involved in the biosynthesis of complex natural products. Those in a subgroup known as "Oxy enzymes" play a crucial role in the biosynthesis of... |
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Disrupting monotony during social isolation stress prevents early development of anxiety and depression like traits in male rats.
BMC Neurosci. 16 , 2, (2015) Although there have been several reports on social isolation induced mood alterations, the independent contribution of monotonous environment in mediating mood alterations has been less studied. In view of the above, the present study is aimed at investigatin... |
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Engineering the genome of Thermus thermophilus using a counterselectable marker.
J. Bacteriol. 197(6) , 1135-44, (2015) Thermus thermophilus is an extremely thermophilic bacterium that is widely used as a model thermophile, in large part due to its amenability to genetic manipulation. Here we describe a system for the introduction of genomic point mutations or deletions using ... |
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Monoamine receptor agonists, acting preferentially at presynaptic autoreceptors and heteroreceptors, downregulate the cell fate adaptor FADD in rat brain cortex.
Neuropharmacology 89 , 204-14, (2014) FADD is a crucial adaptor of death receptors that can engage apoptosis or survival actions (e.g. neuroplasticity) through its phosphorylated form (p-FADD). Although FADD was shown to participate in receptor mechanisms related to drugs of abuse, little is know... |
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Stereoselective synthesis and pharmacological evaluation of [4.3.3]propellan-8-amines as analogs of adamantanamines.
Bioorg. Med. Chem. 23 , 4277-85, (2015) Amantadine (1) exerts its anti-Parkinson effects by inhibition of the NMDA associated cation channel and its antiviral activity by inhibition of the M2 protein channel of influenza A viruses. Herein the synthesis, NMDA receptor affinity and anti-influenza act... |
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Quantitative aspects of electrolysis in electromembrane extractions of acidic and basic analytes.
Anal. Chim. Acta 887 , 92-100, (2015) Electrolysis is omnipresent in all electrochemical processes including electromembrane extraction (EME). The effects of electrolysis on quantitative aspects of EME were comprehensively evaluated for a set of acidic (substituted phenols) and basic (basic drugs... |