Zoxazolamine
Zoxazolamine structure
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Common Name | Zoxazolamine | ||
|---|---|---|---|---|
| CAS Number | 61-80-3 | Molecular Weight | 168.58000 | |
| Density | 1.481 g/cm3 | Boiling Point | 316.8ºC at 760 mmHg | |
| Molecular Formula | C7H5ClN2O | Melting Point | 181-184 °C(lit.) | |
| MSDS | Chinese USA | Flash Point | 145.4ºC | |
| Symbol |
GHS07 |
Signal Word | Warning | |
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Isolation, structure elucidation and in vivo hepatoprotective potential of trans-tetracos-15-enoic acid from Indigofera tinctoria Linn.
Phytother Res. 20(10) , 831-9, (2006) The bioassay guided fractionation of the dried aerial part of Indigofera tinctoria Linn. led to the identification of an active fraction labelled as indigotin. On further chemical analysis, a compound isolated from indigotin was identified and characterized a... |
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Pharmacological activation of cloned intermediate- and small-conductance Ca(2+)-activated K(+) channels.
Am. J. Physiol. 278 , C570-C581, (2000) We previously characterized 1-ethyl-2-benzimidazolinone (1-EBIO), as well as the clinically useful benzoxazoles, chlorzoxazone (CZ), and zoxazolamine (ZOX), as pharmacological activators of the intermediate-conductance Ca(2+)-activated K(+) channel, hIK1. The... |
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Stimulation of Cl(-) secretion by chlorzoxazone.
J. Pharmacol. Exp. Ther. 292 , 778-787, (2000) We previously demonstrated that 1-ethyl-2-benzimidazolone (1-EBIO) directly activates basolateral membrane calcium-activated K(+) channels (K(Ca)), thereby stimulating Cl(-) secretion across several epithelia. In our pursuit to identify potent modulators of C... |
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2-Amino-5-chloro-1,3-benzoxazol-3-ium 2-(3,4-dichlorophenoxy)acetate.
Acta Crystallogr. C 56(Pt 12) , 1478-9, (2000) The 1:1 organic salt of the title compound, C(7)H(6)ClN(2)O(+). C(8)H(5)Cl(2)O(3)(-) or [(2-ABOX)(3,4-D)], comprises the two constituent molecules associated by an R(2)(2)(8) graph-set interaction through the carboxylate group of 3,4-D across the protonated N... |
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The effect of Rhazya stricta Decne, a traditional medicinal plant, on spontaneous and drug-induced alterations in activity of rats.
Pharmacol. Biochem. Behav. 64(3) , 455-60, (1999) The effect of acute and chronic treatment of rats with a lyophilized extract of the leaves of the medicinal plant Rhazya stricta on total and ambulatory activity was studied. Given acutely at single oral doses of 1, 2, 4, and 8 g/kg, the extract produced dose... |
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Effect of intermittent hypobaric hypoxia on efficacy & clearance of drugs.
Indian J. Med. Res. 135 , 211-6, (2012) People travelling to high altitude for occupational, recreational or religious purposes are mostly healthy and fit but sometimes they use drugs for common ailments like influenza, acute mountain sickness or chronic disease like diabetes. Limitation of oxygen ... |
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Acute and subchronic evaluation of Indigofera arrecta: absence of both toxicity and modulation of selected cytochrome P450 isozymes in ddY mice.
Phytother Res. 13(8) , 686-8, (1999) Indigofera arrecta, an anti diabetic plant was investigated in ddY mice to determine its acute and subchronic effects, and whether it modulated hepatic cytochrome P450 (CYP) isozymes and glutathione (GSH). No mortality was observed in the acute (up to 10 g I.... |
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Inhibitory effect of magnolol on Trp-P-2-induced DNA damage in various organs in mice.
Phytother Res. 23(7) , 901-5, (2009) Magnolol has been reported to strongly inhibit the mutagenicity induced by indirect mutagens in the Ames test as well as the clastogenicity induced by benzo(a)pyrene (B(a)P) in the mice micronucleus test. Here, we evaluated the inhibitory effect of magnolol o... |
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Transcription coactivator PRIP, the peroxisome proliferator-activated receptor (PPAR)-interacting protein, is redundant for the function of nuclear receptors PParalpha and CAR, the constitutive androstane receptor, in mouse liver.
Gene Expr. 13(4-5) , 255-69, (2007) Disruption of the genes encoding for the transcription coactivators, peroxisome proliferator-activated receptor (PPAR)-interacting protein (PRIP/ASC-2/RAP250/TRBP/NRC) and PPAR-binding protein (PBP/TRAP220/DRIP205/MED1), results in embryonic lethality by affe... |
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Effect of novel anti-inflammatory ethanolamine derivatives with antioxidant properties on drug metabolising enzymes.
Eur. J. Drug Metab. Pharmacokinet. 28(1) , 7-10, (2003) The influence of four ethanolamine derivatives with anti-inflammatory and antioxidant activity on the in vitro aminopyrine N-demethylation was studied. It was found that these compounds inhibit the N-demethylation of aminopyrine. 1-Cyclohexyl-5-(2-hydroxy-eth... |