LEUCOMALACHITE GREEN

LEUCOMALACHITE GREEN Structure
LEUCOMALACHITE GREEN structure
Common Name LEUCOMALACHITE GREEN
CAS Number 129-73-7 Molecular Weight 330.466
Density 1.1±0.1 g/cm3 Boiling Point 475.4±45.0 °C at 760 mmHg
Molecular Formula C23H26N2 Melting Point 100-102 °C
MSDS Chinese USA Flash Point 214.6±16.5 °C
Symbol GHS08
GHS08
Signal Word Warning

Determination of malachite green, crystal violet and their leuco-metabolites in fish by HPLC-VIS detection after immunoaffinity column clean-up.

J. Chromatogr. B. Analyt. Technol. Biomed. Life Sci. 913-914 , 123-8, (2013)

A high performance liquid chromatography method with visible detection (HPLC-VIS) for the determination of malachite green (MG), crystal violet (CV), leucomalachite green (LMG), and leucocrystal violet (LCV) in fish has been developed after clean-up through a...

Determination of residues of three triphenylmethane dyes and their metabolites (malachite green, leuco malachite green, crystal violet, leuco crystal violet, and brilliant green) in aquaculture products by LC/MS/MS: first action 2012.25.

J. AOAC Int. 96(5) , 1152-7, (2013)

During the AOAC Annual Meeting held from September 30 to October 3, 2012 in Las Vegas, NV, the Expert Review Panel (ERP) on Veterinary Drug Residues reviewed data for the method for determination of residues of three triphenylmethane dyes and their metabolite...

Analysis of sulfonamides, trimethoprim, fluoroquinolones, quinolones, triphenylmethane dyes and methyltestosterone in fish and shrimp using liquid chromatography-mass spectrometry.

J. Chromatogr. B. Analyt. Technol. Biomed. Life Sci. 972 , 38-47, (2014)

A liquid chromatography-tandem mass spectrometry (LC-MS/MS) screening method is described for the detection and identification of 26 veterinary drugs in fish and other aquaculture products. The analytes include: 13 sulfonamides, trimethoprim, 3 fluoroquinolon...

Determination of malachite green residues in fish using molecularly imprinted solid-phase extraction followed by liquid chromatography–linear ion trap mass spectrometry

Anal. Chim. Acta 665(1) , 47-54, (2010)

This paper describes the development of an analytical procedure to determine malachite green (MG) residues in salmon samples using molecularly imprinted polymers (MIPs) as the extraction and clean-up material, followed by liquid chromatography–linear ion trap...

An investigation into the enhancement of fingermarks in blood on fruit and vegetables.

Sci. Justice 53(3) , 321-7, (2013)

A number of studies have reported the successful enhancement of latent fingermarks on fruit and vegetables. A study was set up to identify the most effective technique for the enhancement of fingermarks in blood on various fruit and vegetables. The enhancemen...

Multiclass detection and quantitation of antibiotics and veterinary drugs in shrimps by fast liquid chromatography time-of-flight mass spectrometry.

Talanta 85(3) , 1419-27, (2011)

A fast liquid chromatography time-of-flight mass spectrometry (LC-TOFMS) method has been developed for simultaneous quantitative multiclass determination of residues of selected antibiotics and other veterinary drugs (benzalkonium chloride, ethoxyquin, leucom...

Design and characterization of a direct ELISA for the detection and quantification of leucomalachite green.

Food Addit. Contam. Part A. Chem. Anal. Control. Expo. Risk Assess. 28(6) , 731-9, (2011)

Malachite green (MG), a member of the N-methylated triphenylmethane class of dyes, has long been used to control fungal and protozoan infections in fish. MG is easily absorbed by fish during waterborne exposure and is rapidly metabolized into leucomalachite g...

Chemical enhancement of footwear impressions in blood on fabric - part 2: peroxidase reagents.

Sci. Justice 51(3) , 110-21, (2011)

This study investigates the optimisation of peroxidase based enhancement techniques for footwear impressions made in blood on various fabric surfaces. Four different haem reagents: leuco crystal violet (LCV), leuco malachite green (LMG), fluorescein and lumin...

A simple method for the determination of malachite green and leucomalachite green residues in fish by a modified QuEChERS extraction and LC/MS/MS.

J. AOAC Int. 95(3) , 913-22, (2012)

A simple method using LC/MS/MS was developed and validated to determine residues of malachite green (MG) and leucomalachite green (LMG) in fish fillet. A modified QuEChERS (Quick, Easy, Cheap, Effective, Rugged, and Safe) technique was used to perform the sam...

Evaluation of the developmental toxicity of leucomalachite green administered orally to rats

Food Chem. Toxicol. 49(12) , 3031-7, (2011)

Highlights ► The unmetabolized compound was detected in the plasma of the rat treated with LMG. ► LMG entered the amniotic fluid through the placental barrier. ► LMG at 160mg/kg/day caused embryolethality in rats. ► LMG at 80–160mg/kg/day caused fetal develop...