N,N,N-Tripentyl-1-pentanaminium bromide
N,N,N-Tripentyl-1-pentanaminium bromide structure
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Common Name | N,N,N-Tripentyl-1-pentanaminium bromide | ||
|---|---|---|---|---|
| CAS Number | 866-97-7 | Molecular Weight | 378.474 | |
| Density | 0.92333 g/cm3 (35.00℃) | Boiling Point | N/A | |
| Molecular Formula | C20H44BrN | Melting Point | 100-101ºC(lit.) | |
| MSDS | Chinese USA | Flash Point | N/A | |
| Symbol |
GHS07 |
Signal Word | Warning | |
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KCNE1 reverses the response of the human K+ channel KCNQ1 to cytosolic pH changes and alters its pharmacology and sensitivity to temperature.
Pflugers Arch. 441(2-3) , 368-78, (2000) Previous studies have shown that heteromultimeric KCNQ1/KCNE1 (KvLQT1/minK) channels and homomultimeric KCNQ1 (KvLQT1) channels exhibit different current properties, e.g. distinct kinetics and different sensitivities to drugs. In this study we report on the d... |
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Early-phase occurrence of K+ and Cl- efflux in addition to Ca 2+ mobilization is a prerequisite to apoptosis in HeLa cells.
Apoptosis 17(8) , 821-31, (2012) Sustained rise in cytosolic Ca(2+) and cell shrinkage mainly caused by K(+) and Cl(-) efflux are known to be prerequisites to apoptotic cell death. Here, we investigated how the efflux of K(+) and Cl(-) as well as the rise in cytosolic Ca(2+) occur prior to c... |
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Frequency dependence of alternating current electrospray ionization mass spectrometry.
Anal. Chem. 83(8) , 3017-23, (2011) The novel effects resulting from the entrainment of low mobility ions during alternating current (ac) electrospray ionization are examined through mass spectrometry and voltage/current measurements. Curious phenomena such as pH modulation at high frequencies ... |
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Endothelium-dependent relaxation by tetraoctylammonium ions in rat isolated aortic rings.
Life Sci. 66(1) , PL13-9, (2000) Quaternary ammonium ions are common pharmacological blockers of K+ channels. This study examined the vasorelaxant effect of tetraoctylammonium ions (TOA+) in rat isolated aortic rings. TOA+ caused a concentration-dependent transient relaxation of endothelium-... |
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Effect of urea on the ion-association capillary electrophoresis separation of the anionic metal complexes using hydrophobic tetraalkylammonium as ion-association agent.
Anal. Sci. 26(11) , 1151-6, (2010) The effect of urea as an electrophoretic buffer solution modifier on the ion-association (IA) capillary electrophoresis (CE) separation of four anionic metal complexes of Al(III), Co(III), Cr(III), and Fe(III) with 2,2'-dihydroxyazobenezene-5,5'-disulfonate (... |
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Tetrapentylammonium block of chloramine-T and veratridine modified rat brain type IIA sodium channels.
Br. J. Pharmacol. 132(8) , 1755-60, (2001) Tetrapentylammonium (TPeA) block of rat brain type IIA sodium channel alpha subunit was studied using whole cell patch clamp. Results indicate that TPeA blocks the inactivating brain sodium channel in a potential and use-dependent manner similar to that of th... |
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Quantitative analysis of tetrapentylammonium-induced blockade of open N-methyl-D-aspartate channels.
Biophys. J. 79(3) , 1324-35, (2000) The blockade of open N-methyl-d-aspartate (NMDA) channels by tetrapentylammonium (TPentA) in acutely isolated rat hippocampal neurons was studied using whole-cell patch-clamp techniques. TPentA prevented the closure of the NMDA channel following what is known... |
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State-independent intracellular access of quaternary ammonium blockers to the pore of TREK-1.
Channels (Austin.) 6(6) , 473-8, (2012) We previously reported that TREK-1 gating by internal pH and pressure occurs close to or within the selectivity filter. These conclusions were based upon kinetic measurements of high-affinity block by quaternary ammonium (QA) ions that appeared to exhibit sta... |
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Influence of DNA-dye complex stability on separation resolution in microchip electrophoresis.
Bioanalysis 4(6) , 693-701, (2012) Different markers have been used to label DNA for sample detection in gel electrophoresis. Intercalating dyes, (e.g., YOYO) have been widely used to label DNA for sample detection, because they do not require the use of radioisotopes, covalent attachment or e... |
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Electrophysiological and pharmacological characterization of K+-currents in muscle fibres isolated from the ventral sucker of Fasciola hepatica.
Parasitology 129(Pt 6) , 779-93, (2004) Fibres isolated from the ventral sucker of Fasciola hepatica were identified as muscle on the basis of their contractility, and their actin and myosin staining. They were voltage-clamped at a holding potential of -40 mV and depolarization-activated outward cu... |