Carbendazim

Carbendazim Structure
Carbendazim structure
Common Name Carbendazim
CAS Number 10605-21-7 Molecular Weight 191.187
Density 1.4±0.1 g/cm3 Boiling Point 406.1±28.0 °C at 760 mmHg
Molecular Formula C9H9N3O2 Melting Point >300 °C(lit.)
MSDS Chinese USA Flash Point 199.4±24.0 °C
Symbol GHS08 GHS09
GHS08, GHS09
Signal Word Danger

The complex contributions of genetics and nutrition to immunity in Drosophila melanogaster.

PLoS Genet. 11(3) , e1005030, (2015)

Both malnutrition and undernutrition can lead to compromised immune defense in a diversity of animals, and "nutritional immunology" has been suggested as a means of understanding immunity and determining strategies for fighting infection. The genetic basis fo...

Developing structure-activity relationships for the prediction of hepatotoxicity.

Chem. Res. Toxicol. 23 , 1215-22, (2010)

Drug-induced liver injury is a major issue of concern and has led to the withdrawal of a significant number of marketed drugs. An understanding of structure-activity relationships (SARs) of chemicals can make a significant contribution to the identification o...

A predictive ligand-based Bayesian model for human drug-induced liver injury.

Drug Metab. Dispos. 38 , 2302-8, (2010)

Drug-induced liver injury (DILI) is one of the most important reasons for drug development failure at both preapproval and postapproval stages. There has been increased interest in developing predictive in vivo, in vitro, and in silico models to identify comp...

Coactivator SRC-2-dependent metabolic reprogramming mediates prostate cancer survival and metastasis.

J. Clin. Invest. 125(3) , 1174-88, (2015)

Metabolic pathway reprogramming is a hallmark of cancer cell growth and survival and supports the anabolic and energetic demands of these rapidly dividing cells. The underlying regulators of the tumor metabolic program are not completely understood; however, ...

Activation of mu or delta opioid receptors in the lumbosacral spinal cord is essential for ejaculatory reflexes in male rats.

PLoS ONE 10(3) , e0121130, (2015)

Ejaculation is controlled by a spinal ejaculation generator located in the lumbosacral spinal cord, consisting in male rats of lumbar spinothalamic (LSt) cells and their inter-spinal projections to autonomic and motor centers. LSt cells co-express several neu...

BRAF and MEK inhibition variably affect GD2-specific chimeric antigen receptor (CAR) T-cell function in vitro.

J. Immunother. 38(1) , 12-23, (2014)

Cancer immunotherapy has long been used in the treatment of metastatic melanoma, and an anti-CTLA-4 monoclonal antibody treatment has recently been approved by the US Food and Drug Administration. Targeted therapies such as small molecule kinase inhibitors ta...

Spp24 derivatives stimulate a Gi-protein coupled receptor-Erk1/2 signaling pathway and modulate gene expressions in W-20-17 cells.

J. Cell. Biochem. 116(5) , 767-77, (2015)

Secreted phosphoprotein 24 kDa (Spp24) is an apatite- and BMP/TGF-β cytokine-binding phosphoprotein found in serum and many tissues, including bone. N-terminally intact degradation products ranging in size from 14 kDa to 23 kDa have been found in bone. The cl...

An efficient synthesis of highly functionalized novel chromeno[4,3-b]pyrroles and indolizino[6,7-b]indoles as potent antimicrobial and antioxidant agents.

Bioorg. Med. Chem. Lett. 22 , 1375-9, (2012)

A facile and efficient synthesis of novel chromeno[4,3-b]pyrroles has been accomplished by intramolecular 1,3-dipolar cycloaddition which on subsequent Pictet-Spengler cyclisation in presence of p-toluenesulfonic acid yielded indolizino[6,7-b]indoles. The syn...

Impact of coexistence of carbendazim, atrazine, and imidacloprid on their adsorption, desorption, and mobility in soil.

Environ. Sci. Pollut. Res. Int. 20(9) , 6282-9, (2013)

The effect of coexisting pesticide on adsorption/desorption and mobility of another one was investigated with carbendazim (CBD), imidacloprid (IDP), and atrazine (ATR). The data indicated that adsorption of CBD, ATR, and IDP on the tested soil was fitted well...

Antioxidant and neurotoxicity markers in the model organism Enchytraeus albidus (Oligochaeta): mechanisms of response to atrazine, dimethoate and carbendazim.

Ecotoxicology 23(7) , 1220-33, (2014)

The present study aimed to investigate the effects of dimethoate, atrazine and carbendazim on the antioxidant defences and neuronal function of the soil organism Enchytraeus albidus. Effects were studied at concentrations known to affect their reproduction (E...