cis-(Z)-Flupentixol dihydrochloride
cis-(Z)-Flupentixol dihydrochloride structure
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Common Name | cis-(Z)-Flupentixol dihydrochloride | ||
|---|---|---|---|---|
| CAS Number | 51529-01-2 | Molecular Weight | 507.440 | |
| Density | N/A | Boiling Point | 554.7ºC at 760 mmHg | |
| Molecular Formula | C23H27Cl2F3N2OS | Melting Point | 194-202ºC | |
| MSDS | Chinese USA | Flash Point | 289.3ºC | |
| Symbol |
GHS07 |
Signal Word | Warning | |
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Dopamine receptor antagonists as new mode-of-action insecticide leads for control of Aedes and Culex mosquito vectors.
PLoS Negl. Trop. Dis. 9(3) , e0003515, (2015) New mode-of-action insecticides are sought to provide continued control of pesticide resistant arthropod vectors of neglected tropical diseases (NTDs). We previously identified antagonists of the AaDOP2 D1-like dopamine receptor (DAR) from the yellow fever mo... |
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The nucleus accumbens shell and the dorsolateral striatum mediate the reinforcing effects of cocaine through a serial connection.
Behav. Pharmacol. 26(1-2) , 193-9, (2014) The reinforcing and addictive properties of cocaine are thought to rely on the dopaminergic innervation of the striatum. The ventromedial [i.e. nucleus accumbens shell (NAcc) shell] and dorsolateral [dorsolateral striatum (DLS)] regions of the striatum are se... |
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A screen of approved drugs and molecular probes identifies therapeutics with anti-Ebola virus activity.
Sci. Transl. Med. 7 , 290ra89, (2015) Currently, no approved therapeutics exist to treat or prevent infections induced by Ebola viruses, and recent events have demonstrated an urgent need for rapid discovery of new treatments. Repurposing approved drugs for emerging infections remains a critical ... |
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Orbitofrontal or accumbens dopamine depletion does not affect risk-based decision making in rats.
Cogn. Affect. Behav. Neurosci. 15 , 507-22, (2015) Considerable evidence has implicated dopamine (DA) signals in target regions of midbrain DA neurons such as the medial prefrontal cortex or the core region of the nucleus accumbens in controlling risk-based decision-making. However, to date little is known ab... |
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The dopamine antagonist flupentixol does not alter ghrelin-induced food intake in rats.
Neuropeptides 53 , 19-27, (2015) It has been shown that dopamine antagonists suppress the ghrelin-induced increased motivation to work for food. The aim of this study was to investigate the influence of the dopamine antagonist flupentixol on ghrelin-induced food intake. Ad libitum fed male S... |
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Pharmacological properties of new antipsychotic agents: use of animal models.
Neuropharmacology 20 , 1279-1284, (1981)
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Prolonged neuroleptic effect of alpha-flupenthixol decanoate in oil.
Acta Pharmacol. Toxicol. (Copenh.) 32 , 363-376, (1973)
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