cis-(Z)-Flupentixol dihydrochloride
cis-(Z)-Flupentixol dihydrochloride structure
|
Common Name | cis-(Z)-Flupentixol dihydrochloride | ||
|---|---|---|---|---|
| CAS Number | 51529-01-2 | Molecular Weight | 507.440 | |
| Density | N/A | Boiling Point | 554.7ºC at 760 mmHg | |
| Molecular Formula | C23H27Cl2F3N2OS | Melting Point | 194-202ºC | |
| MSDS | Chinese USA | Flash Point | 289.3ºC | |
| Symbol |
GHS07 |
Signal Word | Warning | |
Use of cis-(Z)-Flupentixol dihydrochloridecis-(Z)-Flupentixol dihydrochloride is a potent and selective DA D1/D2 receptor antagonist, with Ki values of 0.38 nM and 7 nM for D2 receptor and 5-HT2A, respectively[1][2]. |
| Name | Flupenthixol dihydrochloride |
|---|---|
| Synonym | More Synonyms |
| Description | cis-(Z)-Flupentixol dihydrochloride is a potent and selective DA D1/D2 receptor antagonist, with Ki values of 0.38 nM and 7 nM for D2 receptor and 5-HT2A, respectively[1][2]. |
|---|---|
| Related Catalog | |
| Target |
D2 Receptor:0.38 nM (Ki) 5-HT2A Receptor:7 nM (Ki) |
| In Vivo | cis-(Z)-Flupentixol (0.25, or 0.5 mg/kg, i.p.) pretreatment dose-dependently reduces cocaine-induced activity[1]. Animal Model: Rats[1]. Dosage: 0.125, 0.25, or 0.5 mg/kg. Administration: IP. Result: Reduced cocaine-induced activity. |
| References |
| Boiling Point | 554.7ºC at 760 mmHg |
|---|---|
| Melting Point | 194-202ºC |
| Molecular Formula | C23H27Cl2F3N2OS |
| Molecular Weight | 507.440 |
| Flash Point | 289.3ºC |
| Exact Mass | 506.117310 |
| PSA | 52.01000 |
| LogP | 6.08150 |
| Appearance of Characters | white to off-white |
| InChIKey | ZQAWQVWCKYGMNE-CVIBNLPVSA-N |
| SMILES | Cl.OCCN1CCN(CCC=C2c3ccccc3Sc3ccc(C(F)(F)F)cc32)CC1 |
| Storage condition | -20°C Freezer |
| Water Solubility | H2O: soluble |
| Symbol |
GHS07 |
|---|---|
| Signal Word | Warning |
| Hazard Statements | H302 + H312 + H332 |
| Precautionary Statements | P261-P280-P301 + P312 + P330 |
| Personal Protective Equipment | dust mask type N95 (US);Eyeshields;Gloves |
| Hazard Codes | Xn: Harmful; |
| Risk Phrases | R20/21/22 |
| Safety Phrases | S36/37/39 |
| RIDADR | UN 2811 |
| RTECS | TL9900000 |
| HS Code | 2942000000 |
| HS Code | 2942000000 |
|---|
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| flupentixolhydrochloride |
| fx703 |
| cis-(Z)-Flupentixol Dihydrochloride |