2,5-Hexanediol

2,5-Hexanediol Structure
2,5-Hexanediol structure
Common Name 2,5-Hexanediol
CAS Number 2935-44-6 Molecular Weight 118.174
Density 1.0±0.1 g/cm3 Boiling Point 213.4±8.0 °C at 760 mmHg
Molecular Formula C6H14O2 Melting Point N/A
MSDS Chinese USA Flash Point 101.7±0.0 °C
Symbol GHS07
GHS07
Signal Word Warning

Pattern of neurotoxicity of n-hexane, methyl n-butyl ketone, 2,5-hexanediol, and 2,5-hexanedione alone and in combination with O-ethyl O-4-nitrophenyl phenylphosphonothioate in hens.

J. Toxicol. Environ. Health A 16(1) , 85-100, (1985)

This investigation was designed to study the neurotoxicity produced in hens by the aliphatic hexacarbons n-hexane, methyl n-butyl ketone (MnBK), 2,5-hexanediol (2,5-HDOH), and 2,5-hexanedione (2,5-HD) following daily dermal application of each chemical alone ...

The antimycotic activity in vitro of five diols.

Sabouraudia 18(4) , 287-93, (1980)

The antimycotic activity of ethane-1,2-diol, propane-1,2-diol, butane-1,3-diol, pentane-1,5-diol, and hexane-2,5-diol in vitro against Pityrosporum orbiculare, Candida albicans, Trichophyton rubrum, T. mentagrophytes var. interdigitale and Epidermophyton floc...

[Effects of 2,5-hexanediol, 2,4-pentanedione, acetone and 2-heptanone on the secretory responsiveness of the sweat glands in rats (author's transl)].

Sangyo. Igaku. 22(6) , 494-5, (1980)

Highly efficient synthesis of enantiopure diacetylated C(2)-symmetric diols by ruthenium- and enzyme-catalyzed dynamic kinetic asymmetric transformation (DYKAT).

Chemistry 12 , 6053, (2006)

Highly efficient synthesis of enantiopure diacetates of 2,4-pentanediol and 2,5-hexanediol starting from commercially available mixtures of the diols (dl/meso approximately 1:1) has been realized by combining a fast ruthenium-catalyzed epimerization with an e...

Recovery from 2,5-hexanediol intoxication of the retinotectal tract of the rat. An ultrastructural study.

Acta Neuropathol. 58(4) , 286-90, (1982)

Rats were given 2,5-hexanediol, a metabolite of n-hexane, in the drinking water until they developed a marked degree of paresis over about 7 weeks and were then allowed to recover naturally. The time course and the manner of removal of the neurofilamentous ma...

Diastereoselective synthesis of optically active (2 R,5 R)-hexanediol.

Appl. Microbiol. Biotechnol. 58(5) , 595-9, (2002)

Diastereoselective reduction of diketones with Lactobacillus kefir DSM 20587 was examined. The reduction of both oxo-functions proceeded highly diastereoselectively. (2 R,5 R)-Hexanediol 3 was produced starting from (2,5)-hexanedione 1 in quantitative yields ...

Cytochemical staining characteristics of peripheral nodes of Ranvier in hexacarbon intoxication.

J. Neurocytol. 12(3) , 459-73, (1983)

Changes in the distribution of stainable gap substance and subaxolemmal density at peripheral nodes of Ranvier in hexacarbon-intoxicated rats have been studied by light and electron microscopy. Cupric ion binding to the nodal gap substance was seen in normal ...

Interaction between neurotoxicities induced by organophosphorus and long-chain hexacarbon compounds.

Neurotoxicology 4(4) , 117-35, (1983)

Toxicological and metabolic studies of methyl n-butylketone, 2,5-hexanedione, and 2,5-hexanediol in male rats.

Ecotoxicol. Environ. Saf. 3(2) , 204-17, (1979)

Central nervous system effect of 2,5-hexane diol.

Neurotoxicology 6(3) , 53-9, (1985)

Single exposure of 150, 300 and 600 mg/kg 2,5-hexanediol, (2,5 HD) a metabolite of n-hexane showed no significant effect on 3H-spiroperidol binding to corpus striatal membranes when compared with control animals, where as repeated exposure of 2,5-HD, 300 and ...