sodiumiodoacetate
sodiumiodoacetate structure
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Common Name | sodiumiodoacetate | ||
|---|---|---|---|---|
| CAS Number | 305-53-3 | Molecular Weight | 207.930 | |
| Density | N/A | Boiling Point | 262.1ºC at 760mmHg | |
| Molecular Formula | C2H2INaO2 | Melting Point | 208 °C (dec.)(lit.) | |
| MSDS | Chinese USA | Flash Point | 112.3ºC | |
| Symbol |
GHS05, GHS06 |
Signal Word | Danger | |
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Development of a quantitative mass spectrometry multi-attribute method for characterization, quality control testing and disposition of biologics.
MAbs 7 , 881-90, (2015) Regulatory agencies have recently recommended a Quality by Design (QbD) approach for the manufacturing of therapeutic molecules. A QbD strategy requires deep understanding at the molecular level of the attributes that are crucial for safety and efficacy and f... |
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Thrombin-facilitated efflux of D-[3H]-aspartate from cultured astrocytes and neurons under hyponatremia and chemical ischemia.
Neurochem. Res. 39(7) , 1219-31, (2014) Thrombin effect increasing swelling-induced glutamate efflux was examined in cultured cortical astrocytes, cerebellar granule neurons (CGN), hippocampal and cortical neurons. Hypotonic glutamate efflux (monitored by D-[(3)H]aspartate) from cortical astrocytes... |
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Metformin inhibits growth of human glioblastoma cells and enhances therapeutic response.
PLoS ONE 10(4) , e0123721, (2015) High-grade gliomas, glioblastomas (GB), are refractory to conventional treatment combining surgery, chemotherapy, mainly temozolomide, and radiotherapy. This highlights an urgent need to develop novel therapies and increase the efficacy of radio/chemotherapy ... |
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Using lysine-reactive fluorescent dye for surface characterization of a mAb.
J. Pharm. Sci. 104(3) , 995-1004, (2015) The biopharmaceutical industry increasingly demands thorough characterization of protein conformation and conformational dynamics to ensure product quality and consistency. Here, we present a chromatography-based method that is able to characterize protein co... |
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Aceclofenac-loaded chondroitin sulfate conjugated SLNs for effective management of osteoarthritis.
J. Drug Target. 22(9) , 805-12, (2014) Abstract Background: In intra-articular drug delivery, there are number of shortcomings such as lymphatic drainage from the synovial cavity, frequent dosing, adverse side effects and patient discomfort in the management of osteoarthritis (OA).This research wo... |
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An optimized approach to the rapid assessment and detection of sequence variants in recombinant protein products.
Anal. Bioanal. Chem 407(13) , 3851-60, (2015) The development of sensitive techniques to detect sequence variants (SVs), which naturally arise due to DNA mutations and errors in transcription/translation (amino acid misincorporations), has resulted in increased attention to their potential presence in pr... |
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Influence of dietary canola oil and palm oil blend and refrigerated storage on fatty acids, myofibrillar proteins, chemical composition, antioxidant profile and quality attributes of semimembranosus muscle in goats.
J. Anim. Sci. Biotechnol. 6 , 51, (2015) Improving the unsaturated fatty acid content of ruminant meat is essential due to the generally saturated nature of fatty acids in ruminant meat and the negative effects this can have on human health. Nonetheless, enhancing the unsaturated fatty acid content ... |
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Physico-chemical characteristics of Longissimus lumborum muscle in goats subjected to halal slaughter and anesthesia (halothane) pre-slaughter.
Anim. Sci. J. 86 , 981-91, (2015) This study assessed the effect of halal slaughter and anesthesia pre-slaughter followed by bleeding on meat quality characteristics of goats. Eleven male Boer cross goats were divided into two groups and subjected to either halal slaughter (HS) or anesthesia ... |
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Effects of deer bone extract on the expression of pro-inflammatory cytokine and cartilage-related genes in monosodium iodoacetate-induced osteoarthritic rats.
Biosci. Biotechnol. Biochem. 78(10) , 1703-9, (2014) Deer bone extract has the potential to relieve the discomfort or the articular cartilaginous damage associated with osteoarthritic (OA) and may be useful as a natural supplement for OA treatment without serious side effects. We analyzed the expression of pro-... |
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The inimitable kynurenic acid: the roles of different ionotropic receptors in the action of kynurenic acid at a spinal level.
Brain Res. Bull. 112 , 52-60, (2015) Kynurenic acid (KYNA) is a neuroactive metabolite that interacts with NMDA, AMPA/kainate and alpha 7 nicotinic receptors. The goal of this study was to clarify the roles of these receptors in the action of KYNA at a spinal level by using highly specific recep... |