N-Methylpyrrolidone
N-Methylpyrrolidone structure
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Common Name | N-Methylpyrrolidone | ||
|---|---|---|---|---|
| CAS Number | 872-50-4 | Molecular Weight | 99.131 | |
| Density | 1.0±0.1 g/cm3 | Boiling Point | 202.0±0.0 °C at 760 mmHg | |
| Molecular Formula | C5H9NO | Melting Point | −24 °C(lit.) | |
| MSDS | Chinese USA | Flash Point | 86.1±0.0 °C | |
| Symbol |
GHS07, GHS08 |
Signal Word | Danger | |
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Safety and biocompatibility of carbohydrate-functionalized polyanhydride nanoparticles.
AAPS J. 17(1) , 256-67, (2015) Carbohydrate functionalization of nanoparticles allows for targeting of C-type lectin receptors. This family of pattern recognition receptors expressed on innate immune cells, such as macrophages and dendritic cells, can be used to modulate immune responses. ... |
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Hemagglutinin-based polyanhydride nanovaccines against H5N1 influenza elicit protective virus neutralizing titers and cell-mediated immunity.
Int. J. Nanomedicine 10 , 229-43, (2015) H5N1 avian influenza is a significant global concern with the potential to become the next pandemic threat. Recombinant subunit vaccines are an attractive alternative for pandemic vaccines compared to traditional vaccine technologies. In particular, polyanhyd... |
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High-rate aluminium yolk-shell nanoparticle anode for Li-ion battery with long cycle life and ultrahigh capacity.
Nat. Commun. 6 , 7872, (2015) Alloy-type anodes such as silicon and tin are gaining popularity in rechargeable Li-ion batteries, but their rate/cycling capabilities should be improved. Here by making yolk-shell nanocomposite of aluminium core (30 nm in diameter) and TiO2 shell (∼3 nm in t... |
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Quantification of plasma HIV RNA using chemically engineered peptide nucleic acids.
Nat. Commun. 5 , 5079, (2014) The remarkable stability of peptide nucleic acids (PNAs) towards enzymatic degradation makes this class of molecules ideal to develop as part of a diagnostic device. Here we report the development of chemically engineered PNAs for the quantitative detection o... |
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High-Surface-Area Nitrogen-Doped Reduced Graphene Oxide for Electric Double-Layer Capacitors.
ChemSusChem 8 , 1875-84, (2015) A two-step method consisting of solid-state microwave irradiation and heat treatment under NH3 gas was used to prepare nitrogen-doped reduced graphene oxide (N-RGO) with a high specific surface area (1007 m(2) g(-1) ), high electrical conductivity (1532 S m(... |
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Polyanhydride Nanoparticle Delivery Platform Dramatically Enhances Killing of Filarial Worms.
PLoS Negl. Trop. Dis. 9 , e0004173, (2015) Filarial diseases represent a significant social and economic burden to over 120 million people worldwide and are caused by endoparasites that require the presence of symbiotic bacteria of the genus Wolbachia for fertility and viability of the host parasite. ... |
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Sepsis attenuates the anabolic response to skeletal muscle contraction.
Shock 43(4) , 344-51, (2015) Electrically stimulated muscle contraction is a potential clinical therapy to treat sepsis-induced myopathy; however, whether sepsis alters contraction-induced anabolic signaling is unknown. Polymicrobial peritonitis was produced by cecal ligation and punctur... |
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Design, Preparation, and Characterization of Zn and Cu Metallopeptides Based On Tetradentate Aminopyridine Ligands Showing Enhanced DNA Cleavage Activity.
Inorg. Chem. 54 , 10542-58, (2015) The conjugation of redox-active complexes that can function as chemical nucleases to cationic tetrapeptides is pursued in this work in order to explore the expected synergistic effect between these two elements in DNA oxidative cleavage. Coordination complexe... |
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Anticancer effect of black tea extract in human cancer cell lines.
Springerplus 4 , 127, (2015) In this study we investigated effects of natural extract from the black tea Camellia sinensis (BTE) against human colon carcinoma cell line HT-29, human breast carcinoma cell line MCF-7, human alveolar carcinoma cell line A549 and healthy cell line NIH-3T3. W... |
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Carvacrol and rosemary essential oil manifest cytotoxic, DNA-protective and pro-apoptotic effect having no effect on DNA repair.
Neoplasma 61(6) , 690-9, (2014) For several thousand years natural products were successfully used to treat a variety of diseases and to maintain health in humans, but until now it is not fully known what causes these medicinal effects. In our study we assessed the cytotoxic, DNA-protective... |