Epoprostenol sodium
Epoprostenol sodium structure
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Common Name | Epoprostenol sodium | ||
|---|---|---|---|---|
| CAS Number | 61849-14-7 | Molecular Weight | 374.447 | |
| Density | N/A | Boiling Point | 530.2ºC at 760mmHg | |
| Molecular Formula | C20H31NaO5 | Melting Point | 168-170 °C | |
| MSDS | Chinese USA | Flash Point | 182.1ºC | |
| Symbol |
GHS07 |
Signal Word | Warning | |
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Gingival pain: an unusual side effect of ziprasidone.
BMJ Case Rep. 2013 , doi:10.1136/bcr-2012-007577, (2013) The patient is a 52-year-old man with schizophrenia who developed severe, unremitting gingival pain after his ziprasidone dosage was increased from 80 to 120 mg. His physical examination and laboratory findings were unremarkable. He did not have any extra-pyr... |
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PGI₂ signaling inhibits antigen uptake and increases migration of immature dendritic cells.
J. Leukoc. Biol. 94(1) , 77-88, (2013) PGI₂ signaling through IP inhibits allergen-induced inflammatory responses in mice. We reported previously that PGI₂ analogs decreased proinflammatory cytokine and chemokine production by mature BMDCs. However, whether PGI₂ modulates the function of immature ... |
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Human follicular dendritic cells promote germinal center B cell survival by providing prostaglandins.
Mol. Immunol. 55(3-4) , 418-23, (2013) Evidence for the immunoregulatory function of lipid molecules in addition to proteins is accumulating. Based on our previous reports on the production of prostaglandin E₂ (PGE₂) and prostacyclin by human follicular dendritic cells (FDCs), we hypothesized that... |
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Angiotensin 1-7 and Mas decrease thrombosis in Bdkrb2-/- mice by increasing NO and prostacyclin to reduce platelet spreading and glycoprotein VI activation.
Blood 121(15) , 3023-32, (2013) Bradykinin B2 receptor-deleted mice (Bdkrb2(-/-)) have delayed carotid artery thrombosis times and prolonged tail bleeding time resulting from elevated angiotensin II (AngII) and angiotensin receptor 2 (AT2R) producing increased plasma nitric oxide (NO) and p... |
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Inhibition of overactive transforming growth factor-β signaling by prostacyclin analogs in pulmonary arterial hypertension.
Am. J. Respir. Cell. Mol. Biol. 48(6) , 733-41, (2013) The heterozygous loss of function mutations in the Type II bone morphogenetic protein receptor (BMPR-II), a member of the transforming growth factor (TGF-β) receptor family, underlies the majority of familial cases of pulmonary arterial hypertension (PAH). Th... |
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Identification of 14-3-3 proteins in human platelets: effects of synthetic peptides on protein kinase C activation.
Biochem. J. 315 ( Pt 1) , 41-7, (1996) The 14-3-3 proteins inhibit protein kinase C (PKC) activity in vitro and contain conserved sequences that resemble the pseudosubstrate domain of PKC and the C-terminus of the annexins. In the present study we have identified the isoforms of 14-3-3 in human pl... |
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Measurement of kinetic parameters of human platelet DNA polymerase gamma.
Methods 51 , 374-8, (2010) Synthesis of mitochondrial DNA is performed by DNA polymerase gamma. Mutations in POLG, the gene encoding the catalytic subunit of DNA polymerase gamma, are a major cause of neurological disease. A large proportion of patients carry rare nucleotide substituti... |
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Cyclooxygenase-1 and prostacyclin production by endothelial cells in the presence of mild oxidative stress.
PLoS ONE 8(2) , e56683, (2013) This study aimed at evaluating the relative contribution of endothelial cyclooxygenase-1 and -2 (COX-1 and COX-2) to prostacyclin (PGI(2)) production in the presence of mild oxidative stress resulting from autooxidation of polyphenols such as (-)-epigallocate... |
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[Bone marrow edema syndrome (BMES)].
Orthopade. 42(3) , 191-204, (2013) Bone marrow edema (BME) syndrome represents a pathologic accumulation of interstitial fluid in bone - with a traumatic BME being differentiated from a non-traumatic, often ischemic, and a reactive as well as a mechanical BME. Atraumatic/ischemic BME is incons... |
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Improving care for patients with pulmonary hypertension: comment on "Referral of patients with pulmonary hypertension diagnoses to tertiary pulmonary hypertension centers: the multicenter RePHerral study".
JAMA Intern. Med. 173(10) , 893, (2013)
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