HC 067047

HC 067047 Structure
HC 067047 structure
Common Name HC 067047
CAS Number 883031-03-6 Molecular Weight 471.51500
Density N/A Boiling Point N/A
Molecular Formula C26H28F3N3O2 Melting Point N/A
MSDS Chinese USA Flash Point N/A
Symbol GHS06
GHS06
Signal Word Danger

Angiotensin II induces membrane trafficking of natively expressed transient receptor potential vanilloid type 4 channels in hypothalamic 4B cells.

Am. J. Physiol. Regul. Integr. Comp. Physiol. 307(8) , R945-55, (2014)

Transient receptor potential vanilloid family type 4 (TRPV4) channels are expressed in central neuroendocrine neurons and have been shown to be polymodal in other systems. We previously reported that in the rodent, a model of dilutional hyponatremia associate...

Temperature oscillations drive cycles in the activity of MMP-2,9 secreted by a human trabecular meshwork cell line.

Invest. Ophthalmol. Vis. Sci. 56(2) , 1396-405, (2015)

Aqueous humor inflow falls 50% during sleeping hours without proportional fall in IOP, partly reflecting reduced outflow facility. The mechanisms underlying outflow facility cycling are unknown. One outflow facility regulator is matrix metalloproteinase (MMP)...

Role of transient receptor potential and pannexin channels in cigarette smoke-triggered ATP release in the lung.

Thorax 69(12) , 1080-9, (2014)

COPD is an inflammatory disease usually associated with cigarette smoking (CS) with an increasing global prevalence and no effective medication. Extracellular ATP is increased in the COPD affected lung and may play a key role in driving CS-induced airway infl...

The transient receptor potential vanilloid 4 channel modulates uterine tone during pregnancy.

Sci. Transl. Med. 7 , 319ra204, (2015)

The importance of gaining insight into the mechanisms underlying uterine quiescence and contractility is highlighted by the absence of an effective strategy to prevent or treat preterm labor, the greatest cause of perinatal mortality and morbidity worldwide. ...