GDP-ALPHA-D-MANNOSE, DISODIUM SALT
GDP-ALPHA-D-MANNOSE, DISODIUM SALT structure
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Common Name | GDP-ALPHA-D-MANNOSE, DISODIUM SALT | ||
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| CAS Number | 103301-73-1 | Molecular Weight | 649.30 | |
| Density | N/A | Boiling Point | N/A | |
| Molecular Formula | C16H23N5Na2O16P2 | Melting Point | N/A | |
| MSDS | Chinese USA | Flash Point | N/A | |
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Low glucose depletes glycan precursors, reduces site occupancy and galactosylation of a monoclonal antibody in CHO cell culture.
Biotechnol. J. 10 , 1051-66, (2015) Controlled feeding of glucose has been employed previously to enhance the productivity of recombinant glycoproteins but there is a concern that low concentrations of glucose could limit the synthesis of precursors of glycosylation. Here we investigate the eff... |
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Structural and Enzymatic Characterization of a Nucleoside Diphosphate Sugar Hydrolase from Bdellovibrio bacteriovorus.
PLoS ONE 10 , e0141716, (2015) Given the broad range of substrates hydrolyzed by Nudix (nucleoside diphosphate linked to X) enzymes, identification of sequence and structural elements that correctly predict a Nudix substrate or characterize a family is key to correctly annotate the myriad ... |
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Aging without Apolipoprotein D: Molecular and cellular modifications in the hippocampus and cortex.
Exp. Gerontol. 67 , 19-47, (2015) A detailed knowledge of the mechanisms underlying brain aging is fundamental to understand its functional decline and the baseline upon which brain pathologies superimpose. Endogenous protective mechanisms must contribute to the adaptability and plasticity st... |
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L-ascorbic acid biosynthesis.
Vitam. Horm. 61 , 241-266, (2001) Biosynthesis of L-ascorbate (vitamin C) occurs by different pathways in plants and mammals. Yeast contain D-erythroascorbate, a C5 analog of ascorbate. UDP-D-glucuronic acid is the precursor in mammals. Loss of UDP forms glucuronic acid/glucuronolactone. Redu... |
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Identification and characterization of a thermostable bifunctional enzyme with phosphomannose isomerase and sugar-1-phosphate nucleotidylyltransferase activities from a hyperthermophilic archaeon, Pyrococcus horikoshii OT3.
Extremophiles 19 , 1077-85, (2015) Mannosylglycerate is known as a compatible solute, and plays important roles for salinity adaptation and high temperature stability of microorganisms. In the gene cluster for the mannosylglycerate biosynthetic pathway predicted from the genomic data of Pyroco... |
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Characterization of sophorolipid biosynthetic enzymes from Starmerella bombicola.
FEMS Yeast Res. 15 , (2015) Altering glycolipid structure by genetic engineering of Starmerella bombicola is a recently started research topic and worthy alternative to the unsuccessful selective feeding strategies conventionally applied to reach this goal. One question to be addressed ... |
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L-Ascorbic acid metabolism during fruit development in an ascorbate-rich fruit crop chestnut rose (Rosa roxburghii Tratt).
J. Plant Physiol. 171(14) , 1205-16, (2014) Chestnut rose (Rosa roxburghii Tratt) is a fruit crop that contains unusually high levels of l-ascorbic acid (AsA; ∼1300 mg 100g(-1) FW). To explore the mechanisms underlying AsA metabolism, we investigated the distribution and abundance of AsA during fruit d... |
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Identification of a Golgi-localized UDP-N-acetylglucosamine transporter in Trypanosoma cruzi.
BMC Microbiol. 15 , 269, (2015) Nucleotide sugar transporters (NSTs) play an essential role in translocating nucleotide sugars into the lumen of the endoplasmic reticulum and Golgi apparatus to be used as substrates in glycosylation reactions. This intracellular transport is an essential st... |
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Ascorbate biosynthesis and function in photoprotection.
Philos. Trans. R. Soc. Lond., B, Biol. Sci. 355 , 1455-1464, (2000) Ascorbate (vitamin C) can reach very high concentrations in chloroplasts (20-300 mM). The pool size in leaves and chloroplasts increases during acclimation to high light intensity and the highest concentrations recorded are in high alpine plants. Multiple fun... |
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Sugar nucleotide pools of Trypanosoma brucei, Trypanosoma cruzi, and Leishmania major.
Eukaryotic Cell 6 , 1450-1463, (2007) The cell surface glycoconjugates of trypanosomatid parasites are intimately involved in parasite survival, infectivity, and virulence in their insect vectors and mammalian hosts. Although there is a considerable body of work describing their structure, biosyn... |