103301-73-1

103301-73-1 structure

Name: GDP-ALPHA-D-MANNOSE, DISODIUM SALT
Chemical Name: Guanosine 5′-diphospho-D-mannose sodium salt from Saccharomyces cerevisiae
CAS Number: 103301-73-1
Molecular Formula: C₁₆H₂₃N₅Na₂O₁₆P₂
Molecular Weight: 649.30
Catalog: Research Areas Metabolic Disease
Create Date: 2016-05-28 10:35:43
Modify Date: 2024-01-09 19:02:32
GDP-α-D-mannose disodium is the donor substrate for mannosyltransferases and the precursor of GDP-β-L-fucose. GDP-α-D-mannose disodium gives a competitive inhibition with respect to GTP (Ki 14.7 μM) and an uncompetitive inhibition with respect to mannose-1-P (Ki 115 μM)[1].

Name	Guanosine 5′-diphospho-D-mannose sodium salt from Saccharomyces cerevisiae
Synonyms	GDP-α-D-MANNOSE, DISODIUM SALT

Description	GDP-α-D-mannose disodium is the donor substrate for mannosyltransferases and the precursor of GDP-β-L-fucose. GDP-α-D-mannose disodium gives a competitive inhibition with respect to GTP (Ki 14.7 μM) and an uncompetitive inhibition with respect to mannose-1-P (Ki 115 μM)[1].
Related Catalog	Research Areas >> Metabolic Disease
Target	Human Endogenous Metabolite
References	[1]. Elling L, et al. Expression, purification and characterization of recombinant phosphomannomutase and GDP-alpha-D-mannose pyrophosphorylase from Salmonella enterica, group B, for the synthesis of GDP-alpha-D-mannose from D-mannose. Glycobiology. 1996 Sep;6(6):591-7.

Hazard Codes	Xn: Harmful;
Risk Phrases	R22
Safety Phrases	S26
RIDADR	NONH for all modes of transport