GDP-ALPHA-D-MANNOSE, DISODIUM SALT

Modify Date: 2024-01-09 19:02:32

GDP-ALPHA-D-MANNOSE, DISODIUM SALT Structure
GDP-ALPHA-D-MANNOSE, DISODIUM SALT structure
Common Name GDP-ALPHA-D-MANNOSE, DISODIUM SALT
CAS Number 103301-73-1 Molecular Weight 649.30
Density N/A Boiling Point N/A
Molecular Formula C16H23N5Na2O16P2 Melting Point N/A
MSDS Chinese USA Flash Point N/A

 Use of GDP-ALPHA-D-MANNOSE, DISODIUM SALT


GDP-α-D-mannose disodium is the donor substrate for mannosyltransferases and the precursor of GDP-β-L-fucose. GDP-α-D-mannose disodium gives a competitive inhibition with respect to GTP (Ki 14.7 μM) and an uncompetitive inhibition with respect to mannose-1-P (Ki 115 μM)[1].

 Names

Name Guanosine 5′-diphospho-D-mannose sodium salt from Saccharomyces cerevisiae
Synonym More Synonyms

 GDP-ALPHA-D-MANNOSE, DISODIUM SALT Biological Activity

Description GDP-α-D-mannose disodium is the donor substrate for mannosyltransferases and the precursor of GDP-β-L-fucose. GDP-α-D-mannose disodium gives a competitive inhibition with respect to GTP (Ki 14.7 μM) and an uncompetitive inhibition with respect to mannose-1-P (Ki 115 μM)[1].
Related Catalog
Target

Human Endogenous Metabolite

References

[1]. Elling L, et al. Expression, purification and characterization of recombinant phosphomannomutase and GDP-alpha-D-mannose pyrophosphorylase from Salmonella enterica, group B, for the synthesis of GDP-alpha-D-mannose from D-mannose. Glycobiology. 1996 Sep;6(6):591-7.

 Chemical & Physical Properties

Molecular Formula C16H23N5Na2O16P2
Molecular Weight 649.30
Exact Mass 649.04100
PSA 357.00000
Storage condition -20°C

 Safety Information

Hazard Codes Xn: Harmful;
Risk Phrases R22
Safety Phrases S26
RIDADR NONH for all modes of transport

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 Synonyms

GDP-α-D-MANNOSE, DISODIUM SALT