1,4-Dioxane-2,5-dione
1,4-Dioxane-2,5-dione structure
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Common Name | 1,4-Dioxane-2,5-dione | ||
|---|---|---|---|---|
| CAS Number | 502-97-6 | Molecular Weight | 116.07200 | |
| Density | 1.423 g/cm3 | Boiling Point | 322.5ºC at 760 mmHg | |
| Molecular Formula | C4H4O4 | Melting Point | 81-83°C | |
| MSDS | Chinese USA | Flash Point | 181.5ºC | |
| Symbol |
GHS07 |
Signal Word | Warning | |
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Biodegradable lysine-derived polyurethane scaffolds promote healing in a porcine full-thickness excisional wound model.
J. Biomater. Sci. Polym. Ed. 25(17) , 1973-85, (2014) Lysine-derived polyurethane scaffolds (LTI-PUR) support cutaneous wound healing in loose-skinned small animal models. Due to the physiological and anatomical similarities of human and pig skin, we investigated the capacity of LTI-PUR scaffolds to support woun... |
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Microfluidic Synthesis of Hybrid Nanoparticles with Controlled Lipid Layers: Understanding Flexibility-Regulated Cell-Nanoparticle Interaction.
ACS Nano 9 , 9912-21, (2015) The functionalized lipid shell of hybrid nanoparticles plays an important role for improving their biocompatibility and in vivo stability. Yet few efforts have been made to critically examine the shell structure of nanoparticles and its effect on cell-particl... |
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Development and optimization of N-Acetylcysteine-loaded poly (lactic-co-glycolic acid) nanoparticles by electrospray.
Int. J. Biol. Macromol. 72 , 764-70, (2014) N-Acetylcysteine (NAC) loaded PLGA nanoparticles were prepared by electrospray method. The influence of independent parameters such as concentration, flow rate and nozzle to collector distance was studied on particle size and size distribution of generated na... |
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Controlling microencapsulation and release of micronized proteins using poly(ethylene glycol) and electrospraying.
Eur. J. Pharm. Biopharm. 87(2) , 366-77, (2014) The fabrication of tailored microparticles for delivery of therapeutics is a challenge relying upon a complex interplay between processing parameters and materials properties. The emerging use of electrospraying allows better tailoring of particle morphologie... |
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Exendin-4-loaded PLGA microspheres relieve cerebral ischemia/reperfusion injury and neurologic deficits through long-lasting bioactivity-mediated phosphorylated Akt/eNOS signaling in rats.
J. Cereb. Blood Flow Metab. 35 , 1790-803, (2015) Glucagon-like peptide-1 (GLP-1) receptor activation in the brain provides neuroprotection. Exendin-4 (Ex-4), a GLP-1 analog, has seen limited clinical usage because of its short half-life. We developed long-lasting Ex-4-loaded poly(D,L-lactide-co-glycolide) m... |
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3D imaging of cell interactions with electrospun PLGA nanofiber membranes for bone regeneration.
Acta Biomater. 27 , 88-100, (2015) The interaction between resident cells and electrospun nanofibers is critical in determining resultant osteoblast proliferation and activity in orthopedic tissue scaffolds. The use of techniques to evaluate cell-nanofiber interactions is critical in understan... |
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Bio-inspired oligovitronectin-grafted surface for enhanced self-renewal and long-term maintenance of human pluripotent stem cells under feeder-free conditions.
Biomaterials 50 , 127-39, (2015) Current protocols for human pluripotent stem cell (hPSC) expansion require feeder cells or matrices from animal sources that have been the major obstacle to obtain clinical grade hPSCs due to safety issues, difficulty in quality control, and high expense. Thu... |
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Applicability of a newly developed bioassay for determining bioactivity of anti-inflammatory compounds in release studies--celecoxib and triamcinolone acetonide released from novel PLGA-based microspheres.
Pharm. Res. 32(2) , 680-90, (2015) To develop a bio-assay for measuring long-term bioactivity of released anti-inflammatory compounds and to test the bioactivity of celecoxib (CXB) and triamcinolone acetonide (TA) released from a new PLGA-based microsphere platform.Human osteoarthritic chondro... |
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Optimization of a validated stability-indicating RP-LC method for the determination of fulvestrant from polymeric based nanoparticle systems, drugs and biological samples.
Biomed. Chromatogr. 28(10) , 1409-17, (2014) Fulvestrant is used for the treatment of hormone receptor-positive metastatic breast cancer in postmenopausal women with disease progression following anti-estrogen therapy. Several reversed-phase columns with variable silica materials, diameters, lengths, et... |
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Bioactive Hybrid Particles from Poly(D,L-lactide-co-glycolide) Nanoparticle Stabilized Lipid Droplets.
ACS Appl. Mater. Interfaces 7 , 17460-70, (2015) Biodegradable and bioactive hybrid particles composed of poly(D,L-lactide-co-glycolide) (PLGA) nanoparticles and medium-chain triglycerides were prepared by spray drying lipid-in-water emulsions stabilized by PLGA nanoparticles, to form PLGA-lipid hybrid (PLH... |