Guaifenesin
Guaifenesin structure
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Common Name | Guaifenesin | ||
|---|---|---|---|---|
| CAS Number | 93-14-1 | Molecular Weight | 198.216 | |
| Density | 1.2±0.1 g/cm3 | Boiling Point | 356.8±27.0 °C at 760 mmHg | |
| Molecular Formula | C10H14O4 | Melting Point | 77-81 °C | |
| MSDS | Chinese USA | Flash Point | 169.6±23.7 °C | |
| Symbol |
GHS07 |
Signal Word | Warning | |
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Treatment of immune-mediated keratitis in horses with episcleral silicone matrix cyclosporine delivery devices.
Vet. Ophthalmol. 17 Suppl 1 , 23-30, (2014) To describe the use of episcleral silicone matrix cyclosporine (ESMC) drug delivery devices in horses with immune-mediated keratitis (IMMK) with evaluation of tolerability and efficacy in long-term control of inflammation.Retrospective study. ESMC implants (1... |
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Experiment and modeling for the separation of guaifenesin enantiomers using simulated moving bed and Varicol units.
J. Chromatogr. A. 1363 , 242-9, (2014) The separation of guaifenesin enantiomers by both simulated moving bed (SMB) process and Varicol process was investigated experimentally and theoretically, where the columns were packed with cellulose tris 3,5-dimethylphenylcarbamate (Chiralcel OD) stationary... |
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Solubility and some crystallization properties of conglomerate forming chiral drug guaifenesin in water.
J. Pharm. Sci. 103(10) , 3176-82, (2014) The solubility of 3-(2-methoxyphenoxy)-propane-1,2-diol, the well-known chiral drug guaifenesin 1, in water has been investigated by means of polythermal and isothermal approaches. It was found that the solubilities of racemic and enantiomeric diols rac- and ... |
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Question: does guaifenesin improve outcomes in patients with cough associated with upper respiratory infection compared with no intervention?
J. Okla. State Med. Assoc. 105(10) , 397-8, (2012)
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Case report: anaphylactic reaction to guaifenesin.
Hosp. Pract. (Minneap) 37(1) , 60-3, (2009) Adverse drug reactions lead to a significant number of hospital admissions each year and thus contribute to the overall financial burden of health care. Some of these drug reactions are allergic responses. As the overall predictability of allergic responses t... |
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Ephedrine- and guaifenesin-induced nephrolithiasis.
J. Altern. Complement. Med. 10(6) , 967-9, (2004) Ephedrine and guaifenesin are herbal supplements that have experienced increased use over the past decade. Ephedrine has been used as a stimulant and weight-loss product, guaifenesin as an expectorant and cough suppressant; both are found in combination in ma... |
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Guaifenesin in rhinitis.
Curr. Allergy Asthma Rep. 9(2) , 101-6, (2009) Mucus in the airways is a complex mixture of water, lipids, glycoproteins, sugars, and electrolytes that serves as a lubricant for the epithelium. The efficient flow of respiratory mucus is a first level of immune defense that requires an appropriate viscosit... |
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Clinical inquiries. Is guaifenesin safe during pregnancy?
J. Fam. Pract. 56(8) , 669-70, (2007)
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Modulating the synthetase activity of penicillin G acylase in organic media by addition of N-methylimidazole: using vinyl acetate as activated acyl donor.
J. Biotechnol. 153(3-4) , 111-5, (2011) This paper reported the modulation of enzyme activity by organic small molecule. The esterification activity of Penicillin G acylase (PGA) was improved more than 70-fold by the addition of 10% N-methylimidazole. Some control experiments have been designed to ... |
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Identification of aquaporin 4 inhibitors using in vitro and in silico methods.
Bioorg. Med. Chem. 17 , 411-417, (2009) The in vitro inhibitory effects and in silico docking energies of 18 compounds with respect to aquaporin 4 (AQP4) were investigated. More than half of the compounds tested showed inhibitory activity in the in vitro functional assay and included the 5-HT(1B/1D... |