Poly(ethylene glycol)
Poly(ethylene glycol) structure
|
Common Name | Poly(ethylene glycol) | ||
|---|---|---|---|---|
| CAS Number | 25322-68-3 | Molecular Weight | 104.15 | |
| Density | 1.125 | Boiling Point | 250ºC | |
| Molecular Formula | C5H12O2 | Melting Point | -65ºC | |
| MSDS | Chinese USA | Flash Point | 171ºC | |
| Symbol |
GHS06, GHS08, GHS09 |
Signal Word | Danger | |
|
A Comparison of the α2/3/5 Selective Positive Allosteric Modulators L-838,417 and TPA023 in Preclinical Models of Inflammatory and Neuropathic Pain.
Adv. Pharmacol. Sci. 2011 , 608912, (2011) GABA(A) receptors containing α2/3 subunits are current targets in the battle to develop new pain medications, as they are expressed in the spinal cord where increasing inhibitory drive should result in analgesia. However, this approach is prone to a range of ... |
|
|
PDADMAC flocculation of Chinese hamster ovary cells: enabling a centrifuge-less harvest process for monoclonal antibodies.
MAbs 7(2) , 413-28, (2015) High titer (>10 g/L) monoclonal antibody (mAb) cell culture processes are typically achieved by maintaining high viable cell densities over longer culture durations. A corresponding increase in the solids and sub-micron cellular debris particle levels are als... |
|
|
Localized experimental bone metastasis drives osteolysis and sensory hypersensitivity at distant non-tumor-bearing sites.
Breast Cancer Res. Treat. 153 , 9-20, (2015) Patients with breast cancer metastasis to bone suffer from inadequate pain relief. Animal models provide increased understanding of cancer-induced bone and sensory alterations. The objective of this study was to investigate the measures of pain at distant non... |
|
|
CD133 is a marker of bioenergetic stress in human glioma.
PLoS ONE 3 , e3655, (2008) Mitochondria dysfunction and hypoxic microenvironment are hallmarks of cancer cell biology. Recently, many studies have focused on isolation of brain cancer stem cells using CD133 expression. In this study, we investigated whether CD133 expression is regulate... |
|
|
Crosstalk from non-cancerous mitochondria can inhibit tumor properties of metastatic cells by suppressing oncogenic pathways.
PLoS ONE 8 , e61747, (2013) Mitochondrial-nucleus cross talks and mitochondrial retrograde regulation can play a significant role in cellular properties. Transmitochondrial cybrid systems (cybrids) are an excellent tool to study specific effects of altered mitochondria under a defined n... |
|
|
Enhancement of hybridoma formation, clonability and cell proliferation in a nanoparticle-doped aqueous environment.
BMC Biotechnol. 8 , 3, (2008) The isolation and production of human monoclonal antibodies is becoming an increasingly important pursuit as biopharmaceutical companies migrate their drug pipelines away from small organic molecules. As such, optimization of monoclonal antibody technologies ... |
|
|
Design and in vitro evaluation of a novel vaginal drug delivery system based on gelucire.
Curr. Drug Deliv. 6(2) , 159-65, (2009) Carbamazepine indicated for the control of epilepsy, undergoes extensive hepatic first-pass metabolism after oral administration. A vaginal dosage form of carbamazepine is not commercially available. Conventional suppository having poor retention in the vagin... |
|
|
[The prevention of the development of the collagen-induced microembolic syndrome by decreasing the hydrodynamic resistance of the blood with special polymers under flow].
Patol. Fiziol. Eksp. Ter. (4) , 7-9, (1991) The search for antiaggregatory compounds is undertaken, as a rule, under in vitro conditions which do not reflect the dynamics of the real process. The present work deals with study of the peculiarities of the development of the collagen induced microembolic ... |
|
|
Cell–matrix interactions and dynamic mechanical loading influence chondrocyte gene expression and bioactivity in PEG-RGD hydrogels
Acta Biomater. 5(8) , 2832-46, (2009) The pericellular matrix (PCM) surrounding chondrocytes is thought to play an important role in transmitting biochemical and biomechanical signals to the cells, which regulates many cellular functions including tissue homeostasis. To better understand chondroc... |
|
|
Ultrasound monitoring of cartilaginous matrix evolution in degradable PEG hydrogels.
Acta Biomater. 5(1) , 152-61, (2009) Ultrasound has potential as a non-destructive analytical technique to provide real-time online assessments of matrix evolution in cell-hydrogel constructs used in tissue engineering. In these studies, chondrocytes were encapsulated in poly(ethylene glycol) hy... |