cis-4-hydroxy-L-proline
cis-4-hydroxy-L-proline structure
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Common Name | cis-4-hydroxy-L-proline | ||
|---|---|---|---|---|
| CAS Number | 618-27-9 | Molecular Weight | 131.130 | |
| Density | 1.4±0.1 g/cm3 | Boiling Point | 355.2±42.0 °C at 760 mmHg | |
| Molecular Formula | C5H9NO3 | Melting Point | 257ºC | |
| MSDS | Chinese USA | Flash Point | 168.6±27.9 °C | |
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Chemical constituents analysis and antidiabetic activity validation of four fern species from Taiwan.
Int. J. Mol. Sci. 16(2) , 2497-516, (2015) Pterosins are abundant in ferns, and pterosin A was considered a novel activator of adenosine monophosphate-activated protein kinase, which is crucial for regulating blood glucose homeostasis. However, the distribution of pterosins in different species of fer... |
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Liquid exfoliation of solvent-stabilized few-layer black phosphorus for applications beyond electronics.
Nat. Commun. 6 , 8563, (2015) Few-layer black phosphorus (BP) is a new two-dimensional material which is of great interest for applications, mainly in electronics. However, its lack of environmental stability severely limits its synthesis and processing. Here we demonstrate that high-qual... |
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Inhibition of insulin-like growth factor receptor/AKT/mammalian target of rapamycin axis targets colorectal cancer stem cells by attenuating mevalonate-isoprenoid pathway in vitro and in vivo.
Oncotarget 6 , 15332-47, (2015) We observed a co-upregulation of the insulin-like growth factor receptor (IGF-1R)/AKT/mammalian target of rapamycin (mTOR) [InAT] axis and the mevalonate-isoprenoid biosynthesis (MIB) pathways in colorectal cancer stem cells (CSCs) in an unbiased approach. He... |
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New abietane-type diterpene glycosides from the roots of Tripterygium wilfordii.
J. Asian Nat. Prod. Res. 17 , 761-6, (2015) Two new abietane diterpene glycosides, wilfordosides A (1) and B (2), were isolated from the roots of Tripterygium wilfordii. The structures of compounds 1 and 2 were established using spectroscopic methods including extensive 1D and 2D NMR analysis, in combi... |
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Athrombogenic hydrogel coatings for medical devices--Examination of biological properties.
Colloids Surf. B Biointerfaces 130 , 192-8, (2015) In the article the authors present hydrogel coatings prepared from polyvinylpyrrolidone (PVP) macromolecules, which are chemically bonded to polyurethane (PU) substrate. The coating is designed to improve the surface hemocompatibility of blood-contacting medi... |
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Three-dimensional quantitative structure-activity relationship analyses of substrates of the human proton-coupled amino acid transporter 1 (hPAT1).
Bioorg. Med. Chem. 19 , 6409-18, (2011) The proton-coupled amino acid transporter hPAT1 has recently gained much interest due to its ability to transport small drugs thereby allowing their oral administration. A three-dimensional quantitative structure-activity relationship (3D QSAR) study has been... |
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Attenuation of Oxidative Damage by Boerhaavia diffusa L. Against Different Neurotoxic Agents in Rat Brain Homogenate.
J. Diet. Suppl. 13 , 300-12, (2015) Due to a high rate of oxidative metabolic activity in the brain, intense production of reactive oxygen metabolite occurs, and the subsequent generation of free radicals is implicated in the pathogenesis of traumatic brain injury, epilepsy, and ischemia as wel... |
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Ohr Protects Corynebacterium glutamicum against Organic Hydroperoxide Induced Oxidative Stress.
PLoS ONE 10 , e0131634, (2015) Ohr, a bacterial protein encoded by the Organic Hydroperoxide Resistance (ohr) gene, plays a critical role in resistance to organic hydroperoxides. In the present study, we show that the Cys-based thiol-dependent Ohr of Corynebacterium glutamicum decomposes o... |
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Incipient cytotoxicity: A time-independent measure of cytotoxic potency in vitro.
Toxicology 335 , 35-45, (2015) Time is an important determinant of toxicity but largely ignored in in vitro toxicity assays where exposure times chosen are rather arbitrary. To investigate the impact of time on the cytotoxic potency of chemicals in vitro, the concentration dependent cytoto... |
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The role of Arabidopsis glutathione transferase F9 gene under oxidative stress in seedlings.
Acta Biol. Hung. 66 , 406-18, (2015) Arabidopsis thaliana contains 54 soluble glutathione transferases (GSTs, EC 2.5.1.18), which are thought to play major roles in oxidative stress responses, but little is known about the function of individual isoenzymes. The role of AtGST phi 9 (GSTF9) in the... |